Pharmacokinetics and Pharmacodynamics of Tildipirosin Against Pasteurella multocida in a Murine Lung Infection Model

Pharmacokinetics and Pharmacodynamics of Tildipirosin Against Pasteurella multocida in a Murine Lung Infection Model

Tildipirosin, a 16-membered-ring macrolide antimicrobial, has recently been approved for the treatment of swine respiratory disease and bovine respiratory disease. This macrolide is extensively distributed to the site of respiratory infection followed by slow elimination. Clinical efficacy has been...

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Bibliographic Details
Main Authors: Dongping Zeng, Meizhen Sun, Zhoumeng Lin, Miao Li, Ronette Gehring, Zhenling Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Subjects:
tildipirosin
pharmacokinetic/pharmacodynamic (PK/PD)
murine lung infection model
Pasteurella multocida
minimum inhibitory concentration (MIC)
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01038/full

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