Диэлектрофорез эритроцитов в идагностике диффузных заболеваний печени различной этиологии
Electric and viscoelastic parameters of erythrocytes in patients with diffuse liver diseases with different stages and genesis and healthy men were studied by dielectrophoresis. The lowest strain amplitude of erythrocytes, tendency to aggregation, destruction, low resistance, high electrical conduct...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
SINAPS LLC
2011-04-01
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| Series: | Архивъ внутренней медицины |
| Subjects: | |
| Online Access: | https://www.medarhive.ru/jour/article/view/35 |
| Summary: | Electric and viscoelastic parameters of erythrocytes in patients with diffuse liver diseases with different stages and genesis and healthy men were studied by dielectrophoresis. The lowest strain amplitude of erythrocytes, tendency to aggregation, destruction, low resistance, high electrical conductivity of the membranes had thickened red blood cells of patients with mixed etiology of the process, changes were compounded from stage of hepatitis to cirrhosis (p < 0,05). In alcoholic liver disease revealed the greatest differences in the levels of strain amplitude of erythrocytes, polarizability, dipole moment, index of destruction compared to the viral etiology. Chronic HCV-infection leads to large shifts in the parameters of erythrocytes in comparison with HBV (p < 0,001–0,05). Parameters of erythrocytes can be used as an additional criterion for the differential diagnosis, prognosis of the disease, making additional emphasis in the treatment. |
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| ISSN: | 2226-6704 2411-6564 |