Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab
Immune thrombocytopenic purpura (ITP) is one of the complications of systemic lupus erythematosus (SLE). Although corticosteroids are usually selected for initial therapy, some patients are corticosteroid-resistant and, therefore, require other immunosuppressants or splenectomy. However, the best tr...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-10-01
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| Series: | Immunological Medicine |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/25785826.2019.1696644 |
| _version_ | 1819135756627607552 |
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| author | Kazuya Abe Yuichi Ishikawa Junichi Ishikawa Michio Fujiwara Yasuhiko Kita |
| author_facet | Kazuya Abe Yuichi Ishikawa Junichi Ishikawa Michio Fujiwara Yasuhiko Kita |
| author_sort | Kazuya Abe |
| collection | DOAJ |
| description | Immune thrombocytopenic purpura (ITP) is one of the complications of systemic lupus erythematosus (SLE). Although corticosteroids are usually selected for initial therapy, some patients are corticosteroid-resistant and, therefore, require other immunosuppressants or splenectomy. However, the best treatment approach in such patients remains unknown, and there is little evidence regarding which immunosuppressive agent can provide best results. We report the case of a patient with corticosteroid-resistant SLE-associated ITP (SLE-ITP) who was successfully treated with rituximab (RTX). RTX might be a therapeutic option for corticosteroid-resistant SLE-ITP. |
| first_indexed | 2024-12-22T10:24:09Z |
| format | Article |
| id | doaj.art-f3d53afe63514cf095c1edbf83731893 |
| institution | Directory Open Access Journal |
| issn | 2578-5826 |
| language | English |
| last_indexed | 2024-12-22T10:24:09Z |
| publishDate | 2019-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Immunological Medicine |
| spelling | doaj.art-f3d53afe63514cf095c1edbf837318932022-12-21T18:29:32ZengTaylor & Francis GroupImmunological Medicine2578-58262019-10-0142418518810.1080/25785826.2019.16966441696644Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximabKazuya Abe0Yuichi Ishikawa1Junichi Ishikawa2Michio Fujiwara3Yasuhiko Kita4Yokohama Rosai HospitalYokohama Rosai HospitalYokohama Rosai HospitalYokohama Rosai HospitalYokohama Rosai HospitalImmune thrombocytopenic purpura (ITP) is one of the complications of systemic lupus erythematosus (SLE). Although corticosteroids are usually selected for initial therapy, some patients are corticosteroid-resistant and, therefore, require other immunosuppressants or splenectomy. However, the best treatment approach in such patients remains unknown, and there is little evidence regarding which immunosuppressive agent can provide best results. We report the case of a patient with corticosteroid-resistant SLE-associated ITP (SLE-ITP) who was successfully treated with rituximab (RTX). RTX might be a therapeutic option for corticosteroid-resistant SLE-ITP.http://dx.doi.org/10.1080/25785826.2019.1696644systemic lupus erythematosusrituximabimmune thrombocytopenic purpuraantigenscorticosteroids |
| spellingShingle | Kazuya Abe Yuichi Ishikawa Junichi Ishikawa Michio Fujiwara Yasuhiko Kita Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab Immunological Medicine systemic lupus erythematosus rituximab immune thrombocytopenic purpura antigens corticosteroids |
| title | Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab |
| title_full | Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab |
| title_fullStr | Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab |
| title_full_unstemmed | Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab |
| title_short | Successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab |
| title_sort | successful treatment of a patient with refractory immune thrombocytopenic purpura in systemic lupus erythematosus with rituximab |
| topic | systemic lupus erythematosus rituximab immune thrombocytopenic purpura antigens corticosteroids |
| url | http://dx.doi.org/10.1080/25785826.2019.1696644 |
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