Enterococcus faecalis Adapts to Antimicrobial Conjugated Oligoelectrolytes by Lipid Rearrangement and Differential Expression of Membrane Stress Response Genes

Enterococcus faecalis Adapts to Antimicrobial Conjugated Oligoelectrolytes by Lipid Rearrangement and Differential Expression of Membrane Stress Response Genes

Conjugated oligoelectrolytes (COEs) are emerging antimicrobials with broad spectrum activity against Gram positive and Gram negative bacteria as well as fungi. Our previous in vitro evolution studies using Enterococcus faecalis grown in the presence of two related COEs (COE1-3C and COE1-3Py) led to...

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Bibliographic Details
Main Authors: Gayatri Shankar Chilambi, Jamie Hinks, Artur Matysik, Xinyi Zhu, Pei Yi Choo, Xianghui Liu, Mary B. Chan-Park, Guillermo C. Bazan, Kimberly A. Kline, Scott A. Rice
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Microbiology
Subjects:
Enterococcus faecalis
conjugated oligolectrolytes
daptomycin resistance
liaFSR
cell membrane stress response
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00155/full

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