Specialized structural and functional roles of residues selectively conserved in subfamilies of the pleckstrin homology domain family
Homologous domains embedded in multidomain proteins of different domain architectures (DA) may exhibit subtle, but important, differences in their structure and function. Here, we consider two multidomain proteins, Arf nucleotide binding site opener (ARNO) and G protein‐coupled receptor kinase 2 (GR...
Main Authors: | Nagarajan Naveenkumar, Ramanathan Sowdhamini, Narayanaswamy Srinivasan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-11-01
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Series: | FEBS Open Bio |
Subjects: | |
Online Access: | https://doi.org/10.1002/2211-5463.12725 |
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