The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats
The amounts of selenium (Se), iron (Fe), and zinc (Zn) in the liver, kidney, and spleen as a function of age of rats measured using instrumental neutron activation analysis were compared between Se-deficient (SeD) rats and normal rats. The SeD model rats can live for more than 50 weeks. The effect o...
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| Format: | Article |
| Language: | English |
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MDPI AG
2009-11-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/14/11/4440/ |
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| author | Atsushi Hisamatsu Iori Ui Aya Okajo Marie Ariyoshi Sachiyo Terada Ken-ichiro Matsumoto Kazutoyo Endo |
| author_facet | Atsushi Hisamatsu Iori Ui Aya Okajo Marie Ariyoshi Sachiyo Terada Ken-ichiro Matsumoto Kazutoyo Endo |
| author_sort | Atsushi Hisamatsu |
| collection | DOAJ |
| description | The amounts of selenium (Se), iron (Fe), and zinc (Zn) in the liver, kidney, and spleen as a function of age of rats measured using instrumental neutron activation analysis were compared between Se-deficient (SeD) rats and normal rats. The SeD model rats can live for more than 50 weeks. The effect of Se-deficinecy in rats might be weak, compared to the marked malfunction of GSH-Px. The SeD rats can be considered as a model of nonlethal chronic oxidative stress. Fluctuations of Fe and Zn in the liver of Se-deficient rats were observed. The amount of redox-relating minerals, such as Fe and Zn, in SeD rat organs is changeable depending on the age. |
| first_indexed | 2024-12-17T04:51:20Z |
| format | Article |
| id | doaj.art-f3de78792a3c4a8f82c8a1bac73fe2e9 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-17T04:51:20Z |
| publishDate | 2009-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f3de78792a3c4a8f82c8a1bac73fe2e92022-12-21T22:02:54ZengMDPI AGMolecules1420-30492009-11-0114114440445310.3390/molecules14114440The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of RatsAtsushi HisamatsuIori UiAya OkajoMarie AriyoshiSachiyo TeradaKen-ichiro MatsumotoKazutoyo EndoThe amounts of selenium (Se), iron (Fe), and zinc (Zn) in the liver, kidney, and spleen as a function of age of rats measured using instrumental neutron activation analysis were compared between Se-deficient (SeD) rats and normal rats. The SeD model rats can live for more than 50 weeks. The effect of Se-deficinecy in rats might be weak, compared to the marked malfunction of GSH-Px. The SeD rats can be considered as a model of nonlethal chronic oxidative stress. Fluctuations of Fe and Zn in the liver of Se-deficient rats were observed. The amount of redox-relating minerals, such as Fe and Zn, in SeD rat organs is changeable depending on the age.http://www.mdpi.com/1420-3049/14/11/4440/instrumental neutron activation analysisbio-trace elementmineralagingoxidative stress |
| spellingShingle | Atsushi Hisamatsu Iori Ui Aya Okajo Marie Ariyoshi Sachiyo Terada Ken-ichiro Matsumoto Kazutoyo Endo The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats Molecules instrumental neutron activation analysis bio-trace element mineral aging oxidative stress |
| title | The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats |
| title_full | The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats |
| title_fullStr | The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats |
| title_full_unstemmed | The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats |
| title_short | The Effect of Long-Running Severe Selenium-Deficiency on the Amount of Iron and Zinc in the Organs of Rats |
| title_sort | effect of long running severe selenium deficiency on the amount of iron and zinc in the organs of rats |
| topic | instrumental neutron activation analysis bio-trace element mineral aging oxidative stress |
| url | http://www.mdpi.com/1420-3049/14/11/4440/ |
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