FBXO43 increases CCND1 stability to promote hepatocellular carcinoma cell proliferation and migration

FBXO43 increases CCND1 stability to promote hepatocellular carcinoma cell proliferation and migration

Background and AimsAbnormal expression of E3 ubiquitin ligase plays an important role in the development and progression of hepatocellular carcinoma (HCC), although the mechanism has remained elusive. This study aimed to investigate the biological function and potential mechanism of FBXO43 in HCC.Me...

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Bibliographic Details
Main Authors: Chun-Ming Li, Jie Zhang, Wu Wu, Zhu Zhu, Feng Li, Di Wu, Xiao-Jun Wang, Chuan-Ming Xie, Jian-Ping Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
FBXO43
CCND1
hepatocellular carcinoma (HCC)
proliferation
migration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1138348/full

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