Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru
Poultry farming represents Peru’s primary food animal production industry, where antimicrobial growth promoters are still commonly used, exerting selective pressure on intestinal microbial populations. Consumption and direct animal-to-human transmission have been reported, and farmworkers are at hig...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/11/2/190 |
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| author | María Dávalos-Almeyda Agustín Guerrero Germán Medina Alejandra Dávila-Barclay Guillermo Salvatierra Maritza Calderón Robert H. Gilman Pablo Tsukayama |
| author_facet | María Dávalos-Almeyda Agustín Guerrero Germán Medina Alejandra Dávila-Barclay Guillermo Salvatierra Maritza Calderón Robert H. Gilman Pablo Tsukayama |
| author_sort | María Dávalos-Almeyda |
| collection | DOAJ |
| description | Poultry farming represents Peru’s primary food animal production industry, where antimicrobial growth promoters are still commonly used, exerting selective pressure on intestinal microbial populations. Consumption and direct animal-to-human transmission have been reported, and farmworkers are at high risk of colonization with resistant bacteria. We conducted a cross-sectional survey among 54 farmworkers to understand their current antimicrobial resistance (AMR) awareness in Ica, Peru. To gain insight into the potential work-related risk of exposure to bacteria, we also measured the AMR rates in <i>Escherichia coli</i> isolated among 50 broiler chickens. Farmworkers were unaware of antimicrobial resistance (31.5%) or antibiotic resistance (16.7%) terms. Almost two-thirds (61%) consumed antibiotics during the previous month, and only 42.6% received a prescription from a healthcare professional. A total of 107 <i>E. coli</i> chicken isolates were obtained, showing a high frequency of multidrug-resistant (89.7%) and extended-spectrum beta-lactamase (ESBL) production (71.9%). Among ESBL-producer isolates, 84.4% carried the <i>bla</i><sub>CTX-M</sub> gene. Results identified gaps in knowledge that reflect the need for interventions to increase antimicrobial awareness among poultry farmworkers. The high AMR rates among <i>E. coli</i> isolates highlight the need to reduce antimicrobial use in poultry farms. Our findings reveal a critical need for effective policy development and antimicrobial stewardship interventions in poultry production in Ica, Peru. |
| first_indexed | 2024-03-09T22:46:58Z |
| format | Article |
| id | doaj.art-f3e54cea6342456f9418e5bc5a4ab1e4 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-09T22:46:58Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-f3e54cea6342456f9418e5bc5a4ab1e42023-11-23T18:27:57ZengMDPI AGAntibiotics2079-63822022-02-0111219010.3390/antibiotics11020190Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, PeruMaría Dávalos-Almeyda0Agustín Guerrero1Germán Medina2Alejandra Dávila-Barclay3Guillermo Salvatierra4Maritza Calderón5Robert H. Gilman6Pablo Tsukayama7School of Veterinary Medicine, Universidad Nacional San Luis Gonzaga, Ica 11004, PeruSchool of Veterinary Medicine, Universidad Nacional San Luis Gonzaga, Ica 11004, PeruSchool of Veterinary Medicine, Universidad Nacional San Luis Gonzaga, Ica 11004, PeruMicrobial Genomics Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima 15102, PeruMicrobial Genomics Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima 15102, PeruInfectious Diseases Research Laboratories, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima 15102, PeruDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21218, USAMicrobial Genomics Laboratory, Department of Cellular and Molecular Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima 15102, PeruPoultry farming represents Peru’s primary food animal production industry, where antimicrobial growth promoters are still commonly used, exerting selective pressure on intestinal microbial populations. Consumption and direct animal-to-human transmission have been reported, and farmworkers are at high risk of colonization with resistant bacteria. We conducted a cross-sectional survey among 54 farmworkers to understand their current antimicrobial resistance (AMR) awareness in Ica, Peru. To gain insight into the potential work-related risk of exposure to bacteria, we also measured the AMR rates in <i>Escherichia coli</i> isolated among 50 broiler chickens. Farmworkers were unaware of antimicrobial resistance (31.5%) or antibiotic resistance (16.7%) terms. Almost two-thirds (61%) consumed antibiotics during the previous month, and only 42.6% received a prescription from a healthcare professional. A total of 107 <i>E. coli</i> chicken isolates were obtained, showing a high frequency of multidrug-resistant (89.7%) and extended-spectrum beta-lactamase (ESBL) production (71.9%). Among ESBL-producer isolates, 84.4% carried the <i>bla</i><sub>CTX-M</sub> gene. Results identified gaps in knowledge that reflect the need for interventions to increase antimicrobial awareness among poultry farmworkers. The high AMR rates among <i>E. coli</i> isolates highlight the need to reduce antimicrobial use in poultry farms. Our findings reveal a critical need for effective policy development and antimicrobial stewardship interventions in poultry production in Ica, Peru.https://www.mdpi.com/2079-6382/11/2/190AMRpublic awarenessfarmworkersESBLchickengrowth promoters |
| spellingShingle | María Dávalos-Almeyda Agustín Guerrero Germán Medina Alejandra Dávila-Barclay Guillermo Salvatierra Maritza Calderón Robert H. Gilman Pablo Tsukayama Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru Antibiotics AMR public awareness farmworkers ESBL chicken growth promoters |
| title | Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru |
| title_full | Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru |
| title_fullStr | Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru |
| title_full_unstemmed | Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru |
| title_short | Antibiotic Use and Resistance Knowledge Assessment of Personnel on Chicken Farms with High Levels of Antimicrobial Resistance: A Cross-Sectional Survey in Ica, Peru |
| title_sort | antibiotic use and resistance knowledge assessment of personnel on chicken farms with high levels of antimicrobial resistance a cross sectional survey in ica peru |
| topic | AMR public awareness farmworkers ESBL chicken growth promoters |
| url | https://www.mdpi.com/2079-6382/11/2/190 |
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