Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions

Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions

Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due to its sensitive location, surgical resection has high risk and therefore, chemotherapy and radiotherapy are utilized for its treatment. However, chemoresistance and radio-resistance are other problems in GBM t...

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Bibliographic Details
Main Authors: Mehrdad Hashemi, Sara Etemad, Sahar Rezaei, Setayesh Ziaolhagh, Romina Rajabi, Parham Rahmanian, Soheila Abdi, Zeinab Khazaei Koohpar, Reihaneh Rafiei, Behnaz Raei, Fatemeh Ahmadi, Shokooh Salimimoghadam, Amir Reza Aref, Mohammad Arad Zandieh, Maliheh Entezari, Afshin Taheriazam, Kiavash Hushmandi
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Glioblastoma
PTEN/PI3K/Akt
Drug resistance
Prognosis
Non-coding RNAs
Cancer therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222015931

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http://www.sciencedirect.com/science/article/pii/S0753332222015931

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