Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due to its sensitive location, surgical resection has high risk and therefore, chemotherapy and radiotherapy are utilized for its treatment. However, chemoresistance and radio-resistance are other problems in GBM t...
Main Authors: | Mehrdad Hashemi, Sara Etemad, Sahar Rezaei, Setayesh Ziaolhagh, Romina Rajabi, Parham Rahmanian, Soheila Abdi, Zeinab Khazaei Koohpar, Reihaneh Rafiei, Behnaz Raei, Fatemeh Ahmadi, Shokooh Salimimoghadam, Amir Reza Aref, Mohammad Arad Zandieh, Maliheh Entezari, Afshin Taheriazam, Kiavash Hushmandi |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222015931 |
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