Chlorocholine chloride exposure induced spermatogenic dysfunction via iron overload caused by AhR/PERK axis-dependent ferritinophagy activation

Chlorocholine chloride exposure induced spermatogenic dysfunction via iron overload caused by AhR/PERK axis-dependent ferritinophagy activation

Chlorocholine chloride (CCC) is a plant growth regulator used worldwide that is detectable in cereals, fruits and animal products. The health effects of CCC exposure have raised public concern. Our previous research showed that CCC exposure decreased testosterone synthesis in pubertal rats. However,...

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Bibliographic Details
Main Authors:	Wanqian Guo, Chenping Kang, Xiaoxia Wang, Haoran Zhang, Lilan Yuan, Xuetao Wei, Qianqian Xiao, Weidong Hao
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	Chlorocholine chloride (CCC) Spermatogenesis Iron overload Ferritinophagy Endoplasmic reticulum stress (ERS) Aryl hydrocarbon receptor (AhR)
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651324002690

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