Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen

Urachal carcinoma (UC) is a rare tumor mainly affecting middle-aged males. Metastases occur most frequently in lymph nodes and the lungs. There are no standard adjuvant and metastatic treatments. We report the case of a 36-year-old female with UC treated with partial cystectomy who relapsed 3 years...

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Main Authors: Kathleen Dekeister, Jean Louis Viguier, Xavier Martin, Anh Minh Nguyen, Helen Boyle, Aude Flechon
Format: Article
Language:English
Published: Karger Publishers 2016-04-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/444787
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author Kathleen Dekeister
Jean Louis Viguier
Xavier Martin
Anh Minh Nguyen
Helen Boyle
Aude Flechon
author_facet Kathleen Dekeister
Jean Louis Viguier
Xavier Martin
Anh Minh Nguyen
Helen Boyle
Aude Flechon
author_sort Kathleen Dekeister
collection DOAJ
description Urachal carcinoma (UC) is a rare tumor mainly affecting middle-aged males. Metastases occur most frequently in lymph nodes and the lungs. There are no standard adjuvant and metastatic treatments. We report the case of a 36-year-old female with UC treated with partial cystectomy who relapsed 3 years after surgery with left choroidal, lung, mediastinal lymph node, right adrenal, mammary, and bone metastases as well as peritoneal carcinomatosis. She obtained a partial response after 10 cycles of chemotherapy with a modified docetaxel, cisplatin and 5-fluorouracil (mTPF) regimen. This is the first report on the use of the mTPF regimen in UC and on the existence of choroidal, adrenal, and mammary metastases.
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spelling doaj.art-f3ea96d835b443a8ab3d9d67f9f1b96c2022-12-21T23:29:41ZengKarger PublishersCase Reports in Oncology1662-65752016-04-019121622210.1159/000444787444787Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil RegimenKathleen DekeisterJean Louis ViguierXavier MartinAnh Minh NguyenHelen BoyleAude FlechonUrachal carcinoma (UC) is a rare tumor mainly affecting middle-aged males. Metastases occur most frequently in lymph nodes and the lungs. There are no standard adjuvant and metastatic treatments. We report the case of a 36-year-old female with UC treated with partial cystectomy who relapsed 3 years after surgery with left choroidal, lung, mediastinal lymph node, right adrenal, mammary, and bone metastases as well as peritoneal carcinomatosis. She obtained a partial response after 10 cycles of chemotherapy with a modified docetaxel, cisplatin and 5-fluorouracil (mTPF) regimen. This is the first report on the use of the mTPF regimen in UC and on the existence of choroidal, adrenal, and mammary metastases.http://www.karger.com/Article/FullText/444787Urachal carcinomaChoroidal, adrenal, and mammary metastasesModified docetaxel, cisplatin and 5-fluorouracil regimen
spellingShingle Kathleen Dekeister
Jean Louis Viguier
Xavier Martin
Anh Minh Nguyen
Helen Boyle
Aude Flechon
Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen
Case Reports in Oncology
Urachal carcinoma
Choroidal, adrenal, and mammary metastases
Modified docetaxel, cisplatin and 5-fluorouracil regimen
title Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen
title_full Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen
title_fullStr Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen
title_full_unstemmed Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen
title_short Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen
title_sort urachal carcinoma with choroidal lung lymph node adrenal mammary and bone metastases and peritoneal carcinomatosis showing partial response after chemotherapy treatment with a modified docetaxel cisplatin and 5 fluorouracil regimen
topic Urachal carcinoma
Choroidal, adrenal, and mammary metastases
Modified docetaxel, cisplatin and 5-fluorouracil regimen
url http://www.karger.com/Article/FullText/444787
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