<it>In vitro </it>anti-angiogenic properties of LGD1069, a selective retinoid X-receptor agonist through down-regulating Runx2 expression on Human endothelial cells

<it>In vitro </it>anti-angiogenic properties of LGD1069, a selective retinoid X-receptor agonist through down-regulating Runx2 expression on Human endothelial cells

<p>Abstract</p> <p>Background</p> <p>LGD1069 (Targretin<sup>®</sup>) is a selective retinoid X receptor (RXR) ligand, which is used in patients for cutaneous T-cell lymphoma. Our published study reported that LGD1069 inhibited tumor-induced angiogenesis in n...

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Bibliographic Details
Main Authors: Lu Hong, Liu Yu-Hui, Wang Wei, Fu Jianjiang, Luo Yongming
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Cancer
Subjects:
LGD1069
retinoid X receptor
metastasis
angiogenesis
Runx2
Online Access:http://www.biomedcentral.com/1471-2407/11/227

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