Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies
The allostatic load (AL) index constitutes a useful tool to objectively assess the biological aspects of chronic stress in clinical practice. AL index has been positively correlated with cumulative chronic stress (physical and psychosocial stressors) and with a high risk to develop pathological cond...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-06-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00501/full |
| _version_ | 1819010733705265152 |
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| author | Luciana D'Alessio Luciana D'Alessio Guido Pablo Korman Mercedes Sarudiansky Laura Ruth Guelman Laura Scévola Alejandra Pastore Amilcar Obregón Emilio J. A. Roldán |
| author_facet | Luciana D'Alessio Luciana D'Alessio Guido Pablo Korman Mercedes Sarudiansky Laura Ruth Guelman Laura Scévola Alejandra Pastore Amilcar Obregón Emilio J. A. Roldán |
| author_sort | Luciana D'Alessio |
| collection | DOAJ |
| description | The allostatic load (AL) index constitutes a useful tool to objectively assess the biological aspects of chronic stress in clinical practice. AL index has been positively correlated with cumulative chronic stress (physical and psychosocial stressors) and with a high risk to develop pathological conditions (e.g., metabolic syndrome, cardiovascular pathology, inflammatory disorders) and the so-called stress-related psychiatric disorders, including anxiety and depressive disorders. Chronic stress has negative effects on brain neuroplasticity, especially on hippocampal neurogenesis and these effects may be reversed by antidepressant treatments. Several evidences indicate that non-pharmacological interventions based on physical activity and yoga practice may add synergizing benefits to classical treatments (antidepressant and benzodiazepines) for depression and anxiety, reducing the negative effects of chronic stress. The aim of this review is to provide a general overview of current knowledge on AL and chronic stress in relation to depression and anxiety, physical activity and yoga practice. |
| first_indexed | 2024-12-21T01:16:57Z |
| format | Article |
| id | doaj.art-f3ed05b36fb44ea9b0ad2f94333867a4 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-21T01:16:57Z |
| publishDate | 2020-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-f3ed05b36fb44ea9b0ad2f94333867a42022-12-21T19:20:45ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-06-011110.3389/fpsyt.2020.00501520121Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On TherapiesLuciana D'Alessio0Luciana D'Alessio1Guido Pablo Korman2Mercedes Sarudiansky3Laura Ruth Guelman4Laura Scévola5Alejandra Pastore6Amilcar Obregón7Emilio J. A. Roldán8Universidad de Buenos Aires, Facultad de Medicina, IBCN-CONICET, Buenos Aires, ArgentinaUniversidad de Buenos Aires, Hospital Ramos Mejía, Buenos Aires, ArgentinaUniversidad de Buenos Aires, Facultad de Psicología, CAEA-CONICET, Buenos Aires, ArgentinaUniversidad de Buenos Aires, Facultad de Psicología, CAEA-CONICET, Buenos Aires, ArgentinaUniversidad de Buenos Aires, Facultad de Medicina, CEFYBO-CONICET, Buenos Aires, ArgentinaUniversidad de Buenos Aires, Hospital Ramos Mejía, Buenos Aires, ArgentinaDirección Médica y Científica, Gador SA, Buenos Aires, ArgentinaDirección Médica y Científica, Gador SA, Buenos Aires, ArgentinaDirección Médica y Científica, Gador SA, Buenos Aires, ArgentinaThe allostatic load (AL) index constitutes a useful tool to objectively assess the biological aspects of chronic stress in clinical practice. AL index has been positively correlated with cumulative chronic stress (physical and psychosocial stressors) and with a high risk to develop pathological conditions (e.g., metabolic syndrome, cardiovascular pathology, inflammatory disorders) and the so-called stress-related psychiatric disorders, including anxiety and depressive disorders. Chronic stress has negative effects on brain neuroplasticity, especially on hippocampal neurogenesis and these effects may be reversed by antidepressant treatments. Several evidences indicate that non-pharmacological interventions based on physical activity and yoga practice may add synergizing benefits to classical treatments (antidepressant and benzodiazepines) for depression and anxiety, reducing the negative effects of chronic stress. The aim of this review is to provide a general overview of current knowledge on AL and chronic stress in relation to depression and anxiety, physical activity and yoga practice.https://www.frontiersin.org/article/10.3389/fpsyt.2020.00501/fullchronic stressneuroplasticityneurogenesishippocampuscortisolnoradrenaline |
| spellingShingle | Luciana D'Alessio Luciana D'Alessio Guido Pablo Korman Mercedes Sarudiansky Laura Ruth Guelman Laura Scévola Alejandra Pastore Amilcar Obregón Emilio J. A. Roldán Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies Frontiers in Psychiatry chronic stress neuroplasticity neurogenesis hippocampus cortisol noradrenaline |
| title | Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies |
| title_full | Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies |
| title_fullStr | Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies |
| title_full_unstemmed | Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies |
| title_short | Reducing Allostatic Load in Depression and Anxiety Disorders: Physical Activity and Yoga Practice as Add-On Therapies |
| title_sort | reducing allostatic load in depression and anxiety disorders physical activity and yoga practice as add on therapies |
| topic | chronic stress neuroplasticity neurogenesis hippocampus cortisol noradrenaline |
| url | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00501/full |
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