An antibody targeting type III secretion system induces broad protection against Salmonella and Shigella infections.
Salmonella and Shigella bacteria are food- and waterborne pathogens that are responsible for enteric infections in humans and are still the major cause of morbidity and mortality in the emerging countries. The existence of multiple Salmonella and Shigella serotypes as well as the emergence of strain...
Main Authors: | Raphaël Sierocki, Bakhos Jneid, Maria Lucia Orsini Delgado, Marc Plaisance, Bernard Maillère, Hervé Nozach, Stéphanie Simon |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-03-01
|
Series: | PLoS Neglected Tropical Diseases |
Online Access: | https://doi.org/10.1371/journal.pntd.0009231 |
Similar Items
-
Deep mutational engineering of broadly-neutralizing nanobodies accommodating SARS-CoV-1 and 2 antigenic drift
by: Adrien Laroche, et al.
Published: (2022-12-01) -
SipD and IpaD induce a cross-protection against Shigella and Salmonella infections.
by: Bakhos Jneid, et al.
Published: (2020-05-01) -
Role of T3SS-1 SipD Protein in Protecting Mice against Non-typhoidal Salmonella Typhimurium.
by: Bakhos Jneid, et al.
Published: (2016-12-01) -
Combining deep mutational scanning to heatmap of HLA class II binding of immunogenic sequences to preserve functionality and mitigate predicted immunogenicity
by: Coline Sivelle, et al.
Published: (2023-07-01) -
Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold
by: Tiphanie Pruvost, et al.
Published: (2023-12-01)