Physiological Balance of the Body: Theory, Algorithms, and Results

Aim: To confirm algorithm of determination of risk groups with physiological imbalance in the population exposed to unfavorable anthropogenic influences. Methods: The testing included such functional systems as constitution, myocardial contractility, autonomic regulation of the heart rate, regulatio...

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Main Authors: Irina Alchinova, Mikhail Karganov
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Mathematics
Subjects:
Online Access:https://www.mdpi.com/2227-7390/9/3/209
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author Irina Alchinova
Mikhail Karganov
author_facet Irina Alchinova
Mikhail Karganov
author_sort Irina Alchinova
collection DOAJ
description Aim: To confirm algorithm of determination of risk groups with physiological imbalance in the population exposed to unfavorable anthropogenic influences. Methods: The testing included such functional systems as constitution, myocardial contractility, autonomic regulation of the heart rate, regulation of peripheral circulation, psychomotor regulation, respiratory regulation and metabolism. Monitoring is carried out using computerized measurement instrumentation and data processing systems. Results: A risk group with pronounced shifts in the physiological balance was identified, which made up 38% of the surveyed population. The greatest contribution to the imbalance was made by the psychomotor system. Conclusion: We analyzed two different components of organism’s adaptation: resistance and resilience. Physiological systems experiencing increasing load attain a tipping points, where even a weak disturbing influence can induce transition to a qualitatively different state. This transition can result in either recovery of the regulatory stability of the system, or its transition to a lower level (dysregulation) with further development of a pathology. In this regard, of paramount importance is early detection of the signals about approaching the tipping points, one of these is the slowing down phenomenon during functional tests. In view of intricate interaction of physiological systems, recording of as much indicators as possible is advisable. The method of partial correlations is effective for evaluation of adaptive interaction of systems.
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spelling doaj.art-f3f2744b1090430ca2ba5cfe62abf3662023-12-03T14:02:22ZengMDPI AGMathematics2227-73902021-01-019320910.3390/math9030209Physiological Balance of the Body: Theory, Algorithms, and ResultsIrina Alchinova0Mikhail Karganov1Research Institute of General Pathology and Pathophysiology, Baltiyskaya Str. 8, 125315 Moscow, RussiaResearch Institute of General Pathology and Pathophysiology, Baltiyskaya Str. 8, 125315 Moscow, RussiaAim: To confirm algorithm of determination of risk groups with physiological imbalance in the population exposed to unfavorable anthropogenic influences. Methods: The testing included such functional systems as constitution, myocardial contractility, autonomic regulation of the heart rate, regulation of peripheral circulation, psychomotor regulation, respiratory regulation and metabolism. Monitoring is carried out using computerized measurement instrumentation and data processing systems. Results: A risk group with pronounced shifts in the physiological balance was identified, which made up 38% of the surveyed population. The greatest contribution to the imbalance was made by the psychomotor system. Conclusion: We analyzed two different components of organism’s adaptation: resistance and resilience. Physiological systems experiencing increasing load attain a tipping points, where even a weak disturbing influence can induce transition to a qualitatively different state. This transition can result in either recovery of the regulatory stability of the system, or its transition to a lower level (dysregulation) with further development of a pathology. In this regard, of paramount importance is early detection of the signals about approaching the tipping points, one of these is the slowing down phenomenon during functional tests. In view of intricate interaction of physiological systems, recording of as much indicators as possible is advisable. The method of partial correlations is effective for evaluation of adaptive interaction of systems.https://www.mdpi.com/2227-7390/9/3/209adaptive resourceresilienceresistancetipping pointtheory of catastrophes
spellingShingle Irina Alchinova
Mikhail Karganov
Physiological Balance of the Body: Theory, Algorithms, and Results
Mathematics
adaptive resource
resilience
resistance
tipping point
theory of catastrophes
title Physiological Balance of the Body: Theory, Algorithms, and Results
title_full Physiological Balance of the Body: Theory, Algorithms, and Results
title_fullStr Physiological Balance of the Body: Theory, Algorithms, and Results
title_full_unstemmed Physiological Balance of the Body: Theory, Algorithms, and Results
title_short Physiological Balance of the Body: Theory, Algorithms, and Results
title_sort physiological balance of the body theory algorithms and results
topic adaptive resource
resilience
resistance
tipping point
theory of catastrophes
url https://www.mdpi.com/2227-7390/9/3/209
work_keys_str_mv AT irinaalchinova physiologicalbalanceofthebodytheoryalgorithmsandresults
AT mikhailkarganov physiologicalbalanceofthebodytheoryalgorithmsandresults