Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital
Objective: To assess the rise in CKMB and Myoglobin levels and associated factors in non-cardiac patients of ischemic stroke presenting to the Emergency Department of a Tertiary Care Hospital. Study Design: Cross-sectional study. Place and Duration of Study: Department of Emergency Medicine,...
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Format: | Article |
Language: | English |
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Army Medical College Rawalpindi
2022-11-01
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Series: | Pakistan Armed Forces Medical Journal |
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Online Access: | https://www.pafmj.org/index.php/PAFMJ/article/view/6858 |
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author | Muhammad Dawood Yasir Abbas Asif Hashmat Andaleeb Khan Kamil Rehman Butt Shahana Rehman |
author_facet | Muhammad Dawood Yasir Abbas Asif Hashmat Andaleeb Khan Kamil Rehman Butt Shahana Rehman |
author_sort | Muhammad Dawood |
collection | DOAJ |
description |
Objective: To assess the rise in CKMB and Myoglobin levels and associated factors in non-cardiac patients of ischemic stroke presenting to the Emergency Department of a Tertiary Care Hospital.
Study Design: Cross-sectional study.
Place and Duration of Study: Department of Emergency Medicine, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Dec 2020 to May 2021.
Methodology: A total of 150 patients with ischemic stroke diagnosed by the consultant Emergency physician or medical specialist based on clinical and neuro-radiological findings were included in this study. Serum CKMB and myoglobin levels were assessed along with other baseline investigations among the study participants. In addition, the relationship of age, gender, the severity of the stroke and the presence of non-cardiac comorbidities was assessed with the rise in CKMB and myoglobin levels among the target population.
Results: Out of 200 patients with ischemic stroke included in the study, 114(67.0%) were males, while 86(43.0%) were females. 75(37.5%) patients had either raised CKMB or Myoglobin levels, while 125(62.5%) patients had both biomarkers within range. On the National Institutes of Health Stroke Scale, 110(55.0%) patients had mild, 55(22.5%) had mild to moderately severe, 25(12.5%) had severe, and 10(5.0%) had very severe symptoms. Statistical analysis revealed that increased stroke severity had a statistically significant relationship (p-value<0.001) with raised CKMB/Myoglobin levels in the target population.
Conclusion: Raised CKMB or myoglobin levels were found in many patients with acute ischemic stroke. The stroke severity was associated with raised levels of these biomarkers.
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first_indexed | 2024-04-12T05:25:15Z |
format | Article |
id | doaj.art-f3f4d239084f42a193787eddbd1b851a |
institution | Directory Open Access Journal |
issn | 0030-9648 2411-8842 |
language | English |
last_indexed | 2024-04-12T05:25:15Z |
publishDate | 2022-11-01 |
publisher | Army Medical College Rawalpindi |
record_format | Article |
series | Pakistan Armed Forces Medical Journal |
spelling | doaj.art-f3f4d239084f42a193787eddbd1b851a2022-12-22T03:46:20ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422022-11-0172510.51253/pafmj.v72i5.6858Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care HospitalMuhammad Dawood0Yasir Abbas1Asif Hashmat2Andaleeb Khan3Kamil Rehman Butt4Shahana Rehman5Pak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi, PakistanPak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi, PakistanPak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi, PakistanPak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi, PakistanPak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi, PakistanPak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi, Pakistan Objective: To assess the rise in CKMB and Myoglobin levels and associated factors in non-cardiac patients of ischemic stroke presenting to the Emergency Department of a Tertiary Care Hospital. Study Design: Cross-sectional study. Place and Duration of Study: Department of Emergency Medicine, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Dec 2020 to May 2021. Methodology: A total of 150 patients with ischemic stroke diagnosed by the consultant Emergency physician or medical specialist based on clinical and neuro-radiological findings were included in this study. Serum CKMB and myoglobin levels were assessed along with other baseline investigations among the study participants. In addition, the relationship of age, gender, the severity of the stroke and the presence of non-cardiac comorbidities was assessed with the rise in CKMB and myoglobin levels among the target population. Results: Out of 200 patients with ischemic stroke included in the study, 114(67.0%) were males, while 86(43.0%) were females. 75(37.5%) patients had either raised CKMB or Myoglobin levels, while 125(62.5%) patients had both biomarkers within range. On the National Institutes of Health Stroke Scale, 110(55.0%) patients had mild, 55(22.5%) had mild to moderately severe, 25(12.5%) had severe, and 10(5.0%) had very severe symptoms. Statistical analysis revealed that increased stroke severity had a statistically significant relationship (p-value<0.001) with raised CKMB/Myoglobin levels in the target population. Conclusion: Raised CKMB or myoglobin levels were found in many patients with acute ischemic stroke. The stroke severity was associated with raised levels of these biomarkers. https://www.pafmj.org/index.php/PAFMJ/article/view/6858CKMBIschemic strokeMyoglobinNon-cardiac patients |
spellingShingle | Muhammad Dawood Yasir Abbas Asif Hashmat Andaleeb Khan Kamil Rehman Butt Shahana Rehman Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital Pakistan Armed Forces Medical Journal CKMB Ischemic stroke Myoglobin Non-cardiac patients |
title | Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital |
title_full | Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital |
title_fullStr | Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital |
title_full_unstemmed | Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital |
title_short | Rise CKMB and Myoglobin Levels in Non-Cardiac Patients of Ischemic Stroke Presenting to Emergency Department of a Tertiary Care Hospital |
title_sort | rise ckmb and myoglobin levels in non cardiac patients of ischemic stroke presenting to emergency department of a tertiary care hospital |
topic | CKMB Ischemic stroke Myoglobin Non-cardiac patients |
url | https://www.pafmj.org/index.php/PAFMJ/article/view/6858 |
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