Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study
Background & objectives: Pregnant women with dengue infection may be at increased risk of adverse maternal-foetal outcomes. This study was conducted to assess the maternal and perinatal outcomes in women who presented with fever and diagnosed to have dengue infection during pregnancy. Methods: A...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Medical Research |
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| Online Access: | http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2022;volume=156;issue=4;spage=619;epage=623;aulast=Sagili |
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| author | Haritha Sagili R Selva Krishna Rahul Dhodapkar Anish Keepanasseri |
| author_facet | Haritha Sagili R Selva Krishna Rahul Dhodapkar Anish Keepanasseri |
| author_sort | Haritha Sagili |
| collection | DOAJ |
| description | Background & objectives: Pregnant women with dengue infection may be at increased risk of adverse maternal-foetal outcomes. This study was conducted to assess the maternal and perinatal outcomes in women who presented with fever and diagnosed to have dengue infection during pregnancy.
Methods: A retrospective observational study was conducted on pregnant women admitted with fever, in a tertiary referral centre in South India, during January 2015 to December 2018. We compared outcomes of women diagnosed with dengue with that of women without dengue. The study outcomes included pre-term birth, stillbirth, low-birth weight (LBW), maternal mortality and thrombocytopenia.
Results: During the study period, there were six maternal deaths following complications from dengue infection. Higher rates of thrombocytopenia (24.7% vs. 14.6%, P=0.02) were noted among those with recent dengue infection. The risk of still birth was 2.67 [95% confidence interval (CI) 1.09, 6.57], LBW [risk ratio (RR) 1.13, 95% CI 0.87, 1.45] and pre-term birth (RR 1.33, 95% CI 0.89, 1.97) among the cases.
Interpretation & conclusions: Occurrence of adverse maternal and foetal outcomes was increased in pregnant women with fever diagnosed with dengue infection. Future studies are needed to formulate the optimum monitoring and treatment strategies in pregnant women, where dengue can have additive adverse effects to other obstetric complications. |
| first_indexed | 2024-03-13T10:37:34Z |
| format | Article |
| id | doaj.art-f3fc0c6698c94728ac520159e137227e |
| institution | Directory Open Access Journal |
| issn | 0971-5916 |
| language | English |
| last_indexed | 2024-03-13T10:37:34Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Medical Research |
| spelling | doaj.art-f3fc0c6698c94728ac520159e137227e2023-05-18T05:47:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Medical Research0971-59162022-01-01156461962310.4103/ijmr.IJMR_414_20Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational studyHaritha SagiliR Selva KrishnaRahul DhodapkarAnish KeepanasseriBackground & objectives: Pregnant women with dengue infection may be at increased risk of adverse maternal-foetal outcomes. This study was conducted to assess the maternal and perinatal outcomes in women who presented with fever and diagnosed to have dengue infection during pregnancy. Methods: A retrospective observational study was conducted on pregnant women admitted with fever, in a tertiary referral centre in South India, during January 2015 to December 2018. We compared outcomes of women diagnosed with dengue with that of women without dengue. The study outcomes included pre-term birth, stillbirth, low-birth weight (LBW), maternal mortality and thrombocytopenia. Results: During the study period, there were six maternal deaths following complications from dengue infection. Higher rates of thrombocytopenia (24.7% vs. 14.6%, P=0.02) were noted among those with recent dengue infection. The risk of still birth was 2.67 [95% confidence interval (CI) 1.09, 6.57], LBW [risk ratio (RR) 1.13, 95% CI 0.87, 1.45] and pre-term birth (RR 1.33, 95% CI 0.89, 1.97) among the cases. Interpretation & conclusions: Occurrence of adverse maternal and foetal outcomes was increased in pregnant women with fever diagnosed with dengue infection. Future studies are needed to formulate the optimum monitoring and treatment strategies in pregnant women, where dengue can have additive adverse effects to other obstetric complications.http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2022;volume=156;issue=4;spage=619;epage=623;aulast=Sagilidengue infection - maternal mortality - pregnancy – pre-term birth stillbirth – thrombocytopenia |
| spellingShingle | Haritha Sagili R Selva Krishna Rahul Dhodapkar Anish Keepanasseri Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study Indian Journal of Medical Research dengue infection - maternal mortality - pregnancy – pre-term birth stillbirth – thrombocytopenia |
| title | Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study |
| title_full | Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study |
| title_fullStr | Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study |
| title_full_unstemmed | Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study |
| title_short | Maternal & perinatal outcome of fever in pregnancy in the context of dengue - A retrospective observational study |
| title_sort | maternal perinatal outcome of fever in pregnancy in the context of dengue a retrospective observational study |
| topic | dengue infection - maternal mortality - pregnancy – pre-term birth stillbirth – thrombocytopenia |
| url | http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2022;volume=156;issue=4;spage=619;epage=623;aulast=Sagili |
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