Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021

Seasonal influenza is a leading cause of death in the U.S., causing significant morbidity, mortality, and economic burden. Despite the proven efficacy of vaccinations, rates remain notably low, especially among Medicaid enrollees. Leveraging Medicaid claims data, this study characterizes influenza v...

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Main Authors: Behzad Naderalvojoud, Nilpa D. Shah, Jane N. Mutanga, Artur Belov, Rebecca Staiger, Jonathan H. Chen, Barbee Whitaker, Tina Hernandez-Boussard
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/11/11/1712
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author Behzad Naderalvojoud
Nilpa D. Shah
Jane N. Mutanga
Artur Belov
Rebecca Staiger
Jonathan H. Chen
Barbee Whitaker
Tina Hernandez-Boussard
author_facet Behzad Naderalvojoud
Nilpa D. Shah
Jane N. Mutanga
Artur Belov
Rebecca Staiger
Jonathan H. Chen
Barbee Whitaker
Tina Hernandez-Boussard
author_sort Behzad Naderalvojoud
collection DOAJ
description Seasonal influenza is a leading cause of death in the U.S., causing significant morbidity, mortality, and economic burden. Despite the proven efficacy of vaccinations, rates remain notably low, especially among Medicaid enrollees. Leveraging Medicaid claims data, this study characterizes influenza vaccination rates among Medicaid enrollees and aims to elucidate factors influencing vaccine uptake, providing insights that might also be applicable to other vaccine-preventable diseases, including COVID-19. This study used Medicaid claims data from nine U.S. states (2016–2021], encompassing three types of claims: fee-for-service, major Medicaid managed care plan, and combined. We included Medicaid enrollees who had an in-person healthcare encounter during an influenza season in this period, excluding those under 6 months of age, over 65 years, or having telehealth-only encounters. Vaccination was the primary outcome, with secondary outcomes involving in-person healthcare encounters. Chi-square tests, multivariable logistic regression, and Fisher’s exact test were utilized for statistical analysis. A total of 20,868,910 enrollees with at least one healthcare encounter in at least one influenza season were included in the study population between 2016 and 2021. Overall, 15% (N = 3,050,471) of enrollees received an influenza vaccine between 2016 and 2021. During peri-COVID periods, there was an increase in vaccination rates among enrollees compared to pre-COVID periods, from 14% to 16%. Children had the highest influenza vaccination rates among all age groups at 29%, whereas only 17% were of 5–17 years, and 10% were of the 18–64 years were vaccinated. We observed differences in the likelihood of receiving the influenza vaccine among enrollees based on their health conditions and medical encounters. In a study of Medicaid enrollees across nine states, 15% received an influenza vaccine from July 2016 to June 2021. Vaccination rates rose annually, peaking during peri-COVID seasons. The highest uptake was among children (6 months–4 years), and the lowest was in adults (18–64 years). Female gender, urban residency, and Medicaid-managed care affiliation positively influenced uptake. However, mental health and substance abuse disorders decreased the likelihood. This study, reliant on Medicaid claims data, underscores the need for outreach services.
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spelling doaj.art-f3fd681c0a7b47099a3af985271685c72023-11-24T15:10:14ZengMDPI AGVaccines2076-393X2023-11-011111171210.3390/vaccines11111712Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021Behzad Naderalvojoud0Nilpa D. Shah1Jane N. Mutanga2Artur Belov3Rebecca Staiger4Jonathan H. Chen5Barbee Whitaker6Tina Hernandez-Boussard7Department of Medicine, Stanford University, Stanford, CA 94305, USADepartment of Medicine, Stanford University, Stanford, CA 94305, USACenter for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, U.S. Food and Drug Administration, Silver Spring, MD 20993, USACenter for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, U.S. Food and Drug Administration, Silver Spring, MD 20993, USADepartment of Medicine, Stanford University, Stanford, CA 94305, USADepartment of Medicine, Stanford University, Stanford, CA 94305, USACenter for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, U.S. Food and Drug Administration, Silver Spring, MD 20993, USADepartment of Medicine, Stanford University, Stanford, CA 94305, USASeasonal influenza is a leading cause of death in the U.S., causing significant morbidity, mortality, and economic burden. Despite the proven efficacy of vaccinations, rates remain notably low, especially among Medicaid enrollees. Leveraging Medicaid claims data, this study characterizes influenza vaccination rates among Medicaid enrollees and aims to elucidate factors influencing vaccine uptake, providing insights that might also be applicable to other vaccine-preventable diseases, including COVID-19. This study used Medicaid claims data from nine U.S. states (2016–2021], encompassing three types of claims: fee-for-service, major Medicaid managed care plan, and combined. We included Medicaid enrollees who had an in-person healthcare encounter during an influenza season in this period, excluding those under 6 months of age, over 65 years, or having telehealth-only encounters. Vaccination was the primary outcome, with secondary outcomes involving in-person healthcare encounters. Chi-square tests, multivariable logistic regression, and Fisher’s exact test were utilized for statistical analysis. A total of 20,868,910 enrollees with at least one healthcare encounter in at least one influenza season were included in the study population between 2016 and 2021. Overall, 15% (N = 3,050,471) of enrollees received an influenza vaccine between 2016 and 2021. During peri-COVID periods, there was an increase in vaccination rates among enrollees compared to pre-COVID periods, from 14% to 16%. Children had the highest influenza vaccination rates among all age groups at 29%, whereas only 17% were of 5–17 years, and 10% were of the 18–64 years were vaccinated. We observed differences in the likelihood of receiving the influenza vaccine among enrollees based on their health conditions and medical encounters. In a study of Medicaid enrollees across nine states, 15% received an influenza vaccine from July 2016 to June 2021. Vaccination rates rose annually, peaking during peri-COVID seasons. The highest uptake was among children (6 months–4 years), and the lowest was in adults (18–64 years). Female gender, urban residency, and Medicaid-managed care affiliation positively influenced uptake. However, mental health and substance abuse disorders decreased the likelihood. This study, reliant on Medicaid claims data, underscores the need for outreach services.https://www.mdpi.com/2076-393X/11/11/1712influenza vaccinevaccineMedicaidCOVID-19vaccination uptake
spellingShingle Behzad Naderalvojoud
Nilpa D. Shah
Jane N. Mutanga
Artur Belov
Rebecca Staiger
Jonathan H. Chen
Barbee Whitaker
Tina Hernandez-Boussard
Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021
Vaccines
influenza vaccine
vaccine
Medicaid
COVID-19
vaccination uptake
title Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021
title_full Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021
title_fullStr Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021
title_full_unstemmed Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021
title_short Trends in Influenza Vaccination Rates among a Medicaid Population from 2016 to 2021
title_sort trends in influenza vaccination rates among a medicaid population from 2016 to 2021
topic influenza vaccine
vaccine
Medicaid
COVID-19
vaccination uptake
url https://www.mdpi.com/2076-393X/11/11/1712
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