The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review

This review was conducted to emphasize the complex interplay between atrial fibrillation (AF) and myocardial infraction (MI). In type 1 (T1) MI, AF is frequent and associated with excess mortality. Moreover, AF after hospital discharge for T1MI is not rare, suggesting the need to improve AF screenin...

Full description

Bibliographic Details
Main Authors: Alban Belkouche, Hermann Yao, Alain Putot, Frédéric Chagué, Luc Rochette, Nicolas Danchin, Laurent Fauchier, Marianne Zeller, Yves Cottin
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/2/198
_version_ 1797415067534229504
author Alban Belkouche
Hermann Yao
Alain Putot
Frédéric Chagué
Luc Rochette
Nicolas Danchin
Laurent Fauchier
Marianne Zeller
Yves Cottin
author_facet Alban Belkouche
Hermann Yao
Alain Putot
Frédéric Chagué
Luc Rochette
Nicolas Danchin
Laurent Fauchier
Marianne Zeller
Yves Cottin
author_sort Alban Belkouche
collection DOAJ
description This review was conducted to emphasize the complex interplay between atrial fibrillation (AF) and myocardial infraction (MI). In type 1 (T1) MI, AF is frequent and associated with excess mortality. Moreover, AF after hospital discharge for T1MI is not rare, suggesting the need to improve AF screening and to develop therapeutic strategies for AF recurrence. Additionally, AF is a common trigger for type 2 MI (T2MI), and recent data have shown that tachyarrhythmia or bradyarrhythmia could be a causal factor in, respectively, 13–47% or 2–7% of T2MI. In addition, AF is involved in T2MI pathogenesis as a result of severe anemia related to anticoagulants. AF is also an underestimated and frequent cause of coronary artery embolism (CE), as a situation at risk of myocardial infarction with non-obstructive coronary arteries. AF-causing CE is difficult to diagnose and requires specific management. Moreover, patients with both AF and chronic coronary syndromes represent a therapeutic challenge because the treatment of AF include anticoagulation, depending on the embolic risk, and ischemic heart disease management paradoxically includes antiplatelet therapy.
first_indexed 2024-03-09T05:42:42Z
format Article
id doaj.art-f40ca0be2aa043cf98d9d01a6a06b456
institution Directory Open Access Journal
issn 2077-0383
language English
last_indexed 2024-03-09T05:42:42Z
publishDate 2021-01-01
publisher MDPI AG
record_format Article
series Journal of Clinical Medicine
spelling doaj.art-f40ca0be2aa043cf98d9d01a6a06b4562023-12-03T12:24:08ZengMDPI AGJournal of Clinical Medicine2077-03832021-01-0110219810.3390/jcm10020198The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A ReviewAlban Belkouche0Hermann Yao1Alain Putot2Frédéric Chagué3Luc Rochette4Nicolas Danchin5Laurent Fauchier6Marianne Zeller7Yves Cottin8Department of Cardiology, University Teaching Hospital of Dijon Bourgogne, 21000 Dijon, FranceDepartment of Cardiology, University Teaching Hospital of Dijon Bourgogne, 21000 Dijon, FranceDepartment of Geriatry, University Teaching Hospital Dijon Bourgogne, 21000 Dijon, FranceDepartment of Cardiology, University Teaching Hospital of Dijon Bourgogne, 21000 Dijon, FranceTeam PEC2, EA 7460, University of Burgundy, 21078 Dijon, FranceDepartment of Cardiology, University Teaching Hospital of Georges Pompidou, 75015 Paris, FranceDepartment of Cardiology, University Teaching Hospital of Trousseau and University François Rabelais, 37000 Tours, FranceTeam PEC2, EA 7460, University of Burgundy, 21078 Dijon, FranceDepartment of Cardiology, University Teaching Hospital of Dijon Bourgogne, 21000 Dijon, FranceThis review was conducted to emphasize the complex interplay between atrial fibrillation (AF) and myocardial infraction (MI). In type 1 (T1) MI, AF is frequent and associated with excess mortality. Moreover, AF after hospital discharge for T1MI is not rare, suggesting the need to improve AF screening and to develop therapeutic strategies for AF recurrence. Additionally, AF is a common trigger for type 2 MI (T2MI), and recent data have shown that tachyarrhythmia or bradyarrhythmia could be a causal factor in, respectively, 13–47% or 2–7% of T2MI. In addition, AF is involved in T2MI pathogenesis as a result of severe anemia related to anticoagulants. AF is also an underestimated and frequent cause of coronary artery embolism (CE), as a situation at risk of myocardial infarction with non-obstructive coronary arteries. AF-causing CE is difficult to diagnose and requires specific management. Moreover, patients with both AF and chronic coronary syndromes represent a therapeutic challenge because the treatment of AF include anticoagulation, depending on the embolic risk, and ischemic heart disease management paradoxically includes antiplatelet therapy.https://www.mdpi.com/2077-0383/10/2/198atrial fibrillationchronic coronary syndromebleedingtype 1 and type 2 myocardial infarction
spellingShingle Alban Belkouche
Hermann Yao
Alain Putot
Frédéric Chagué
Luc Rochette
Nicolas Danchin
Laurent Fauchier
Marianne Zeller
Yves Cottin
The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
Journal of Clinical Medicine
atrial fibrillation
chronic coronary syndrome
bleeding
type 1 and type 2 myocardial infarction
title The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
title_full The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
title_fullStr The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
title_full_unstemmed The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
title_short The Multifaceted Interplay between Atrial Fibrillation and Myocardial Infarction: A Review
title_sort multifaceted interplay between atrial fibrillation and myocardial infarction a review
topic atrial fibrillation
chronic coronary syndrome
bleeding
type 1 and type 2 myocardial infarction
url https://www.mdpi.com/2077-0383/10/2/198
work_keys_str_mv AT albanbelkouche themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT hermannyao themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT alainputot themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT fredericchague themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT lucrochette themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT nicolasdanchin themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT laurentfauchier themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT mariannezeller themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT yvescottin themultifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT albanbelkouche multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT hermannyao multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT alainputot multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT fredericchague multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT lucrochette multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT nicolasdanchin multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT laurentfauchier multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT mariannezeller multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview
AT yvescottin multifacetedinterplaybetweenatrialfibrillationandmyocardialinfarctionareview