Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>)
The distribution of pyrethroid insecticide deltamethrin (DLM) in goat milk and cheese (caciotta) following pour-on administration at the sheep dosage (DLMS-10 mL/60 kg body weight) and double dosage (DLMD-20 mL/60 kg body weight) was studied. DLM concentrations were measured in milk collected from s...
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| Format: | Article |
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MDPI AG
2019-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/24/3/517 |
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| author | Raffaele Marrone Abilasha Ramkumar Giorgio Smaldone Domenico Rufrano Claudia Chirollo Vincenzo Veneziano Martin Danaher Aniello Anastasio |
| author_facet | Raffaele Marrone Abilasha Ramkumar Giorgio Smaldone Domenico Rufrano Claudia Chirollo Vincenzo Veneziano Martin Danaher Aniello Anastasio |
| author_sort | Raffaele Marrone |
| collection | DOAJ |
| description | The distribution of pyrethroid insecticide deltamethrin (DLM) in goat milk and cheese (caciotta) following pour-on administration at the sheep dosage (DLMS-10 mL/60 kg body weight) and double dosage (DLMD-20 mL/60 kg body weight) was studied. DLM concentrations were measured in milk collected from study animals (No.14) before treatment and at 2, 4, 8, 12, 16, 24, 30, 36, 48, 56, until 168 h (7 days) post treatment and in caciotta cheese at 12 and 24 h post treatment. At both dosages, the maximum level of DLM residues in goat milk and cheese was below the maximum residue limit (MRL) of 20 μg kg<sup>−1</sup> established for bovine milk (EU No 37/2010) at all time points. However, in terms of public health, higher DLM residues in cheese show that further specific studies should be performed on double dosage efficacy and pharmacokinetic and pharmacodynamics properties of ectoparasites in lactating goats. |
| first_indexed | 2024-04-12T05:37:15Z |
| format | Article |
| id | doaj.art-f40e34855b2f4f698231c9e63b19bca0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-12T05:37:15Z |
| publishDate | 2019-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f40e34855b2f4f698231c9e63b19bca02022-12-22T03:45:49ZengMDPI AGMolecules1420-30492019-01-0124351710.3390/molecules24030517molecules24030517Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>)Raffaele Marrone0Abilasha Ramkumar1Giorgio Smaldone2Domenico Rufrano3Claudia Chirollo4Vincenzo Veneziano5Martin Danaher6Aniello Anastasio7Department of Veterinary Medicine and Animal Production, University of Naples ‘‘Federico II’’ Via F. Delpino, 1-80137 Naples, ItalyFood Safety Department, Teagasc Food Research Centre Ashtown, Dublin 15, D15 DY05 Dublin 15, IrelandDepartment of Veterinary Medicine and Animal Production, University of Naples ‘‘Federico II’’ Via F. Delpino, 1-80137 Naples, ItalyResearch Unit for the Extensive Animal Husbandry, CRA ZOE, Muro Lucano (PZ), 85054 Muro Lucano, ItalyDepartment of Veterinary Medicine and Animal Production, University of Naples ‘‘Federico II’’ Via F. Delpino, 1-80137 Naples, ItalyDepartment of Veterinary Medicine and Animal Production, University of Naples ‘‘Federico II’’ Via F. Delpino, 1-80137 Naples, ItalyFood Safety Department, Teagasc Food Research Centre Ashtown, Dublin 15, D15 DY05 Dublin 15, IrelandDepartment of Veterinary Medicine and Animal Production, University of Naples ‘‘Federico II’’ Via F. Delpino, 1-80137 Naples, ItalyThe distribution of pyrethroid insecticide deltamethrin (DLM) in goat milk and cheese (caciotta) following pour-on administration at the sheep dosage (DLMS-10 mL/60 kg body weight) and double dosage (DLMD-20 mL/60 kg body weight) was studied. DLM concentrations were measured in milk collected from study animals (No.14) before treatment and at 2, 4, 8, 12, 16, 24, 30, 36, 48, 56, until 168 h (7 days) post treatment and in caciotta cheese at 12 and 24 h post treatment. At both dosages, the maximum level of DLM residues in goat milk and cheese was below the maximum residue limit (MRL) of 20 μg kg<sup>−1</sup> established for bovine milk (EU No 37/2010) at all time points. However, in terms of public health, higher DLM residues in cheese show that further specific studies should be performed on double dosage efficacy and pharmacokinetic and pharmacodynamics properties of ectoparasites in lactating goats.https://www.mdpi.com/1420-3049/24/3/517ectoparasitespyrethroidwithdrawal periodUHPLC-MS/MS |
| spellingShingle | Raffaele Marrone Abilasha Ramkumar Giorgio Smaldone Domenico Rufrano Claudia Chirollo Vincenzo Veneziano Martin Danaher Aniello Anastasio Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>) Molecules ectoparasites pyrethroid withdrawal period UHPLC-MS/MS |
| title | Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>) |
| title_full | Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>) |
| title_fullStr | Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>) |
| title_full_unstemmed | Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>) |
| title_short | Deltamethrin Residues in Milk and Cheese of Lactating Goats (<i>Capra hircus</i>) |
| title_sort | deltamethrin residues in milk and cheese of lactating goats i capra hircus i |
| topic | ectoparasites pyrethroid withdrawal period UHPLC-MS/MS |
| url | https://www.mdpi.com/1420-3049/24/3/517 |
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