Spatiotemporal organisation of protein processing in the kidney
Polesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states.
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33469-5 |
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author | Marcello Polesel Monika Kaminska Dominik Haenni Milica Bugarski Claus Schuh Nevena Jankovic Andres Kaech Jose M. Mateos Marine Berquez Andrew M. Hall |
author_facet | Marcello Polesel Monika Kaminska Dominik Haenni Milica Bugarski Claus Schuh Nevena Jankovic Andres Kaech Jose M. Mateos Marine Berquez Andrew M. Hall |
author_sort | Marcello Polesel |
collection | DOAJ |
description | Polesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states. |
first_indexed | 2024-12-10T04:03:44Z |
format | Article |
id | doaj.art-f41312183e8b4308832408e2902d0b62 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-10T04:03:44Z |
publishDate | 2022-09-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-f41312183e8b4308832408e2902d0b622022-12-22T02:02:54ZengNature PortfolioNature Communications2041-17232022-09-0113111310.1038/s41467-022-33469-5Spatiotemporal organisation of protein processing in the kidneyMarcello Polesel0Monika Kaminska1Dominik Haenni2Milica Bugarski3Claus Schuh4Nevena Jankovic5Andres Kaech6Jose M. Mateos7Marine Berquez8Andrew M. Hall9Institute of Anatomy, University of ZurichInstitute of Anatomy, University of ZurichCenter for Microscopy and Image Analysis, University of ZurichInstitute of Anatomy, University of ZurichInstitute of Anatomy, University of ZurichInstitute of Anatomy, University of ZurichCenter for Microscopy and Image Analysis, University of ZurichCenter for Microscopy and Image Analysis, University of ZurichInstitute of Physiology, University of ZurichInstitute of Anatomy, University of ZurichPolesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states.https://doi.org/10.1038/s41467-022-33469-5 |
spellingShingle | Marcello Polesel Monika Kaminska Dominik Haenni Milica Bugarski Claus Schuh Nevena Jankovic Andres Kaech Jose M. Mateos Marine Berquez Andrew M. Hall Spatiotemporal organisation of protein processing in the kidney Nature Communications |
title | Spatiotemporal organisation of protein processing in the kidney |
title_full | Spatiotemporal organisation of protein processing in the kidney |
title_fullStr | Spatiotemporal organisation of protein processing in the kidney |
title_full_unstemmed | Spatiotemporal organisation of protein processing in the kidney |
title_short | Spatiotemporal organisation of protein processing in the kidney |
title_sort | spatiotemporal organisation of protein processing in the kidney |
url | https://doi.org/10.1038/s41467-022-33469-5 |
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