Spatiotemporal organisation of protein processing in the kidney

Polesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states.

Bibliographic Details
Main Authors: Marcello Polesel, Monika Kaminska, Dominik Haenni, Milica Bugarski, Claus Schuh, Nevena Jankovic, Andres Kaech, Jose M. Mateos, Marine Berquez, Andrew M. Hall
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33469-5
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author Marcello Polesel
Monika Kaminska
Dominik Haenni
Milica Bugarski
Claus Schuh
Nevena Jankovic
Andres Kaech
Jose M. Mateos
Marine Berquez
Andrew M. Hall
author_facet Marcello Polesel
Monika Kaminska
Dominik Haenni
Milica Bugarski
Claus Schuh
Nevena Jankovic
Andres Kaech
Jose M. Mateos
Marine Berquez
Andrew M. Hall
author_sort Marcello Polesel
collection DOAJ
description Polesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states.
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language English
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spelling doaj.art-f41312183e8b4308832408e2902d0b622022-12-22T02:02:54ZengNature PortfolioNature Communications2041-17232022-09-0113111310.1038/s41467-022-33469-5Spatiotemporal organisation of protein processing in the kidneyMarcello Polesel0Monika Kaminska1Dominik Haenni2Milica Bugarski3Claus Schuh4Nevena Jankovic5Andres Kaech6Jose M. Mateos7Marine Berquez8Andrew M. Hall9Institute of Anatomy, University of ZurichInstitute of Anatomy, University of ZurichCenter for Microscopy and Image Analysis, University of ZurichInstitute of Anatomy, University of ZurichInstitute of Anatomy, University of ZurichInstitute of Anatomy, University of ZurichCenter for Microscopy and Image Analysis, University of ZurichCenter for Microscopy and Image Analysis, University of ZurichInstitute of Physiology, University of ZurichInstitute of Anatomy, University of ZurichPolesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states.https://doi.org/10.1038/s41467-022-33469-5
spellingShingle Marcello Polesel
Monika Kaminska
Dominik Haenni
Milica Bugarski
Claus Schuh
Nevena Jankovic
Andres Kaech
Jose M. Mateos
Marine Berquez
Andrew M. Hall
Spatiotemporal organisation of protein processing in the kidney
Nature Communications
title Spatiotemporal organisation of protein processing in the kidney
title_full Spatiotemporal organisation of protein processing in the kidney
title_fullStr Spatiotemporal organisation of protein processing in the kidney
title_full_unstemmed Spatiotemporal organisation of protein processing in the kidney
title_short Spatiotemporal organisation of protein processing in the kidney
title_sort spatiotemporal organisation of protein processing in the kidney
url https://doi.org/10.1038/s41467-022-33469-5
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