A Virus-like Particle-Based F4 Enterotoxigenic <i>Escherichia coli</i> Vaccine Is Inhibited by Maternally Derived Antibodies in Piglets but Generates Robust Responses in Sows

A Virus-like Particle-Based F4 Enterotoxigenic <i>Escherichia coli</i> Vaccine Is Inhibited by Maternally Derived Antibodies in Piglets but Generates Robust Responses in Sows

F4-positive enterotoxigenic <i>Escherichia coli</i> is associated with diarrhea and poor growth outcomes in neonatal and newly weaned piglets and is thus a major economic and welfare burden in the swine industry. Vaccination of sows with F4 fimbriae protects against the neonatal disease...

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Bibliographic Details
Main Authors: Kara-Lee Aves, Priscila R. Guerra, Ana H. Fresno, Mauro M. S. Saraiva, Eric Cox, Poul J. Bækbo, Morten A. Nielsen, Adam F. Sander, John E. Olsen
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pathogens
Subjects:
F4+ enterotoxigenic <i>E. coli</i>
post-weaning diarrhea
virus-like particle
FaeG
Stb toxin
maternal antibody inhibition
Online Access:https://www.mdpi.com/2076-0817/12/12/1388

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