Can leucine supplementation attenuate muscle atrophy? A literature review
Currently, there has been new expectations in studying strategies with the potential to mitigate the skeletal muscle atrophy that characterizes conditions such as aging, disuse, cancer, and the use of certain medications. Among them, amino acid leucine has received special attention due to its poten...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universidade Federal de Santa Catarina
2015-07-01
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| Series: | Revista Brasileira de Cineantropometria e Desempenho Humano |
| Subjects: | |
| Online Access: | https://periodicos.ufsc.br/index.php/rbcdh/article/view/36471 |
| _version_ | 1818288140096372736 |
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| author | Rafael Bruno Do Amaral Carlos Eduardo Carvalho Martins Antonio Herbert Lancha Junior Vitor de Salles Painelli |
| author_facet | Rafael Bruno Do Amaral Carlos Eduardo Carvalho Martins Antonio Herbert Lancha Junior Vitor de Salles Painelli |
| author_sort | Rafael Bruno Do Amaral |
| collection | DOAJ |
| description | Currently, there has been new expectations in studying strategies with the potential to mitigate the skeletal muscle atrophy that characterizes conditions such as aging, disuse, cancer, and the use of certain medications. Among them, amino acid leucine has received special attention due to its potential to stimulate specific pathways of protein synthesis in skeletal muscle. Due to the wide spread use of this amino acid by the media, several studies have been aimed at investigating the possible effectiveness of leucine against skeletal muscle atrophy. As a result, this literature review was aimed to analyze recent studies that investigated the effects of leucine supplementation on skeletal muscle atrophy in both humans and animals. Overall, the wide variations in the experimental designs developed, models studied, leucine dose, treatment duration and sample healthiness make it difficult for professionals and researchers to establish guidelines about possible therapeutic effectiveness of this nutritional strategy. |
| first_indexed | 2024-12-13T01:51:39Z |
| format | Article |
| id | doaj.art-f416353234764083a39a525c353d3580 |
| institution | Directory Open Access Journal |
| issn | 1415-8426 1980-0037 |
| language | English |
| last_indexed | 2024-12-13T01:51:39Z |
| publishDate | 2015-07-01 |
| publisher | Universidade Federal de Santa Catarina |
| record_format | Article |
| series | Revista Brasileira de Cineantropometria e Desempenho Humano |
| spelling | doaj.art-f416353234764083a39a525c353d35802022-12-22T00:03:31ZengUniversidade Federal de Santa CatarinaRevista Brasileira de Cineantropometria e Desempenho Humano1415-84261980-00372015-07-0117449650610.5007/1980-0037.2015v17n4p49623995Can leucine supplementation attenuate muscle atrophy? A literature reviewRafael Bruno Do Amaral0Carlos Eduardo Carvalho Martins1Antonio Herbert Lancha Junior2Vitor de Salles Painelli3University of São Paulo.University of São Paulo.University of São Paulo.University of São Paulo.Currently, there has been new expectations in studying strategies with the potential to mitigate the skeletal muscle atrophy that characterizes conditions such as aging, disuse, cancer, and the use of certain medications. Among them, amino acid leucine has received special attention due to its potential to stimulate specific pathways of protein synthesis in skeletal muscle. Due to the wide spread use of this amino acid by the media, several studies have been aimed at investigating the possible effectiveness of leucine against skeletal muscle atrophy. As a result, this literature review was aimed to analyze recent studies that investigated the effects of leucine supplementation on skeletal muscle atrophy in both humans and animals. Overall, the wide variations in the experimental designs developed, models studied, leucine dose, treatment duration and sample healthiness make it difficult for professionals and researchers to establish guidelines about possible therapeutic effectiveness of this nutritional strategy.https://periodicos.ufsc.br/index.php/rbcdh/article/view/36471atrofia muscularleucinasuplementos dietéticosuso terapêutico |
| spellingShingle | Rafael Bruno Do Amaral Carlos Eduardo Carvalho Martins Antonio Herbert Lancha Junior Vitor de Salles Painelli Can leucine supplementation attenuate muscle atrophy? A literature review Revista Brasileira de Cineantropometria e Desempenho Humano atrofia muscular leucina suplementos dietéticos uso terapêutico |
| title | Can leucine supplementation attenuate muscle atrophy? A literature review |
| title_full | Can leucine supplementation attenuate muscle atrophy? A literature review |
| title_fullStr | Can leucine supplementation attenuate muscle atrophy? A literature review |
| title_full_unstemmed | Can leucine supplementation attenuate muscle atrophy? A literature review |
| title_short | Can leucine supplementation attenuate muscle atrophy? A literature review |
| title_sort | can leucine supplementation attenuate muscle atrophy a literature review |
| topic | atrofia muscular leucina suplementos dietéticos uso terapêutico |
| url | https://periodicos.ufsc.br/index.php/rbcdh/article/view/36471 |
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