Analysis of pathohistological characteristics of pterygium
Pterygium internum (external eye layer) shows great recurrence tendency after surgical removal. Its etiology is still unclear and represents a significant problem. The main goal of our study was to explore the interrelationships of pathohistological characteristics of pterygium, namely presence of i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2010-11-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/2677 |
| _version_ | 1797260856945278976 |
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| author | Boban Džunić Predrag Jovanović Dragan Veselinović Aleksandar Petrović Ivan Stefanović Igor Kovačević |
| author_facet | Boban Džunić Predrag Jovanović Dragan Veselinović Aleksandar Petrović Ivan Stefanović Igor Kovačević |
| author_sort | Boban Džunić |
| collection | DOAJ |
| description | Pterygium internum (external eye layer) shows great recurrence tendency after surgical removal. Its etiology is still unclear and represents a significant problem. The main goal of our study was to explore the interrelationships of pathohistological characteristics of pterygium, namely presence of inflammation, vascularisation degree and fibrinoid changes and on the basis of their analysis to test the possibility of predicting its evolution and recurrence. The analysis was performed on the material taken from 55 patients surgically treated by the technique of Arlt. The specimens were stained using the classical histochemical methods: hematoxylin-eosin (HE), Masson’s trichrome, Gomori’s reticulin stain and PAS technique. Pterygium is mostly covered by conjunctival epithelium, while in the cap region shows morphology of modified stratified squamous epithelium of the cornea. Structural basis of the epithelium is composed of continuous basal lamina and continuous connective fibers underneath. This connective basis shows fibrinoid changes in the form of oval islets of different size, parallel to convexity of pterygium, or is in the form of unified focus. The number, caliber and the type of blood vessels showed excessive variability.
Pathohistological analysis of morphological characteristics of pterygium is adequate basis for prediction of recurrences; as they present the biggest concern in treatment of this widely spread disease.
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| first_indexed | 2024-04-24T23:31:59Z |
| format | Article |
| id | doaj.art-f416ec2be054476a803e7b9850b060b5 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:31:59Z |
| publishDate | 2010-11-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-f416ec2be054476a803e7b9850b060b52024-03-15T14:34:45ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2010-11-0110410.17305/bjbms.2010.2677403Analysis of pathohistological characteristics of pterygiumBoban Džunić0Predrag Jovanović1Dragan Veselinović2Aleksandar Petrović3Ivan Stefanović4Igor Kovačević5Ophthalmology Clinic, Clinical CenterOphthalmology Clinic, Clinical CenterOphthalmology Clinic, Clinical CenterInstitute of Hystology and Embryology, Faculty of MedicineInstitute for Eye Diseases, Clinical CenterInstitute for Eye Diseases, Clinical CenterPterygium internum (external eye layer) shows great recurrence tendency after surgical removal. Its etiology is still unclear and represents a significant problem. The main goal of our study was to explore the interrelationships of pathohistological characteristics of pterygium, namely presence of inflammation, vascularisation degree and fibrinoid changes and on the basis of their analysis to test the possibility of predicting its evolution and recurrence. The analysis was performed on the material taken from 55 patients surgically treated by the technique of Arlt. The specimens were stained using the classical histochemical methods: hematoxylin-eosin (HE), Masson’s trichrome, Gomori’s reticulin stain and PAS technique. Pterygium is mostly covered by conjunctival epithelium, while in the cap region shows morphology of modified stratified squamous epithelium of the cornea. Structural basis of the epithelium is composed of continuous basal lamina and continuous connective fibers underneath. This connective basis shows fibrinoid changes in the form of oval islets of different size, parallel to convexity of pterygium, or is in the form of unified focus. The number, caliber and the type of blood vessels showed excessive variability. Pathohistological analysis of morphological characteristics of pterygium is adequate basis for prediction of recurrences; as they present the biggest concern in treatment of this widely spread disease. https://www.bjbms.org/ojs/index.php/bjbms/article/view/2677pterygiumrecurrencepathohistological characteristics |
| spellingShingle | Boban Džunić Predrag Jovanović Dragan Veselinović Aleksandar Petrović Ivan Stefanović Igor Kovačević Analysis of pathohistological characteristics of pterygium Biomolecules & Biomedicine pterygium recurrence pathohistological characteristics |
| title | Analysis of pathohistological characteristics of pterygium |
| title_full | Analysis of pathohistological characteristics of pterygium |
| title_fullStr | Analysis of pathohistological characteristics of pterygium |
| title_full_unstemmed | Analysis of pathohistological characteristics of pterygium |
| title_short | Analysis of pathohistological characteristics of pterygium |
| title_sort | analysis of pathohistological characteristics of pterygium |
| topic | pterygium recurrence pathohistological characteristics |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/2677 |
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