Identification, Cloning and Heterologous Expression of the Gene Cluster Directing RES-701-3, -4 Lasso Peptides Biosynthesis from a Marine <i>Streptomyces</i> Strain

RES-701-3 and RES-701-4 are two class II lasso peptides originally identified in the fermentation broth of <i>Streptomyces</i> sp. RE-896, which have been described as selective endothelin type B receptor antagonists. These two lasso peptides only differ in the identity of the C-terminal...

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Bibliographic Details
Main Authors: Daniel Oves-Costales, Marina Sánchez-Hidalgo, Jesús Martín, Olga Genilloud
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/18/5/238

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