Prior Binge Ethanol Exposure Potentiates the Microglial Response in a Model of Alcohol-Induced Neurodegeneration

Prior Binge Ethanol Exposure Potentiates the Microglial Response in a Model of Alcohol-Induced Neurodegeneration

Excessive alcohol consumption results in neurodegeneration which some hypothesize is caused by neuroinflammation. One characteristic of neuroinflammation is microglial activation, but it is now well accepted that microglial activation may be pro- or anti-inflammatory. Recent work indicates that the...

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Bibliographic Details
Main Authors:	Simon Alex Marshall, Chelsea Rhea Geil, Kimberly Nixon
Format:	Article
Language:	English
Published:	MDPI AG 2016-05-01
Series:	Brain Sciences
Subjects:	alcohol ethanol microglia cytokines TNF-alpha alcoholism microglial priming neurodegeneration
Online Access:	http://www.mdpi.com/2076-3425/6/2/16

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