Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors
Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors d...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-01-01
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| Series: | npj Flexible Electronics |
| Online Access: | https://doi.org/10.1038/s41528-018-0047-8 |
| _version_ | 1818425693042638848 |
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| author | Emil R. Mamleyev Stefan Heissler Alexei Nefedov Peter G. Weidler Nurdiana Nordin Vladislav V. Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma |
| author_facet | Emil R. Mamleyev Stefan Heissler Alexei Nefedov Peter G. Weidler Nurdiana Nordin Vladislav V. Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma |
| author_sort | Emil R. Mamleyev |
| collection | DOAJ |
| description | Highly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors directly convert commercially available Kapton films into carbon using IR laser, and optimize the process for obtaining a high surface area material with hydrophilic functional groups for biosensor fabrication. These inexpensive flexible sensors are fabricated by enzyme absorption on to the carbon films, with or without an electrodeposited intermediate chitosan layer. They can be rolled-up to fit inside a catheter tube, and feature detection limit down to 10−4 M urea concentration that is 100 times lower than that in the blood serum of a healthy human. These sensors show promising applications as they are inexpensive, flexible, readily usable for in-vivo urea determination and easily extendable to multi- functional circuits. |
| first_indexed | 2024-12-14T14:17:59Z |
| format | Article |
| id | doaj.art-f41f532e51e849fe90a029d41465439c |
| institution | Directory Open Access Journal |
| issn | 2397-4621 |
| language | English |
| last_indexed | 2024-12-14T14:17:59Z |
| publishDate | 2019-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Flexible Electronics |
| spelling | doaj.art-f41f532e51e849fe90a029d41465439c2022-12-21T22:58:09ZengNature Portfolionpj Flexible Electronics2397-46212019-01-013111110.1038/s41528-018-0047-8Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensorsEmil R. Mamleyev0Stefan Heissler1Alexei Nefedov2Peter G. Weidler3Nurdiana Nordin4Vladislav V. Kudryashov5Kerstin Länge6Neil MacKinnon7Swati Sharma8Institute of Microstructure Technology, Karlsruhe Institute of TechnologyInstitute of Functional Interfaces, Karlsruhe Institute of TechnologyInstitute of Functional Interfaces, Karlsruhe Institute of TechnologyInstitute of Functional Interfaces, Karlsruhe Institute of TechnologyInstitute of Microstructure Technology, Karlsruhe Institute of TechnologyInstitute of Nuclear PhysicsInstitute of Microstructure Technology, Karlsruhe Institute of TechnologyInstitute of Microstructure Technology, Karlsruhe Institute of TechnologyInstitute of Microstructure Technology, Karlsruhe Institute of TechnologyHighly sensitive urea sensors can now be made with direct infrared laser writing on cheap Kapton sheets A collaborative international team led by Dr. Swati Sharma from Karlsruhe Institute of Technology, Germany demonstrates the first catheter-compatible, pH-based enzymatic urea sensor. The authors directly convert commercially available Kapton films into carbon using IR laser, and optimize the process for obtaining a high surface area material with hydrophilic functional groups for biosensor fabrication. These inexpensive flexible sensors are fabricated by enzyme absorption on to the carbon films, with or without an electrodeposited intermediate chitosan layer. They can be rolled-up to fit inside a catheter tube, and feature detection limit down to 10−4 M urea concentration that is 100 times lower than that in the blood serum of a healthy human. These sensors show promising applications as they are inexpensive, flexible, readily usable for in-vivo urea determination and easily extendable to multi- functional circuits.https://doi.org/10.1038/s41528-018-0047-8 |
| spellingShingle | Emil R. Mamleyev Stefan Heissler Alexei Nefedov Peter G. Weidler Nurdiana Nordin Vladislav V. Kudryashov Kerstin Länge Neil MacKinnon Swati Sharma Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors npj Flexible Electronics |
| title | Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
| title_full | Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
| title_fullStr | Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
| title_full_unstemmed | Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
| title_short | Laser-induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
| title_sort | laser induced hierarchical carbon patterns on polyimide substrates for flexible urea sensors |
| url | https://doi.org/10.1038/s41528-018-0047-8 |
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