Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma
Some rare malignant diseases exhibit clinical features and bone marrow aspirate morphology similar to that of acute leukemia. For instance, rhabdomyosarcoma, neuroblastoma, medulloblastoma, anaplastic oligodendroglioma, small cell carcinoma, Ewings sarcoma and neuroendocrine tumors have been reporte...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2018-12-01
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| Series: | Medicine Science |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=295505 |
| _version_ | 1827361311642615808 |
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| author | Sinan Demircioglu Omer Ekinci Ali Dogan Irfan Bayram Cengiz Demir |
| author_facet | Sinan Demircioglu Omer Ekinci Ali Dogan Irfan Bayram Cengiz Demir |
| author_sort | Sinan Demircioglu |
| collection | DOAJ |
| description | Some rare malignant diseases exhibit clinical features and bone marrow aspirate morphology similar to that of acute leukemia. For instance, rhabdomyosarcoma, neuroblastoma, medulloblastoma, anaplastic oligodendroglioma, small cell carcinoma, Ewings sarcoma and neuroendocrine tumors have been reported to display an acute leukemia-like morphology in bone marrow aspirates after metastasizing to the bone marrow. Rhabdomyosarcoma (RMS), a malignant tumour of mesenchymal origin which can occur at various sites in the body, is one of the most common soft tissue sarcomas in both children and adolescents, but is rare in adults with a prevalence of less than 1 %. Bone marrow metastases associated with this condition may be readily confused with acute leukemia or lymphoma. Diagnostic confirmation requires immunohistochemical and flowcytometric examinations. In patients with positive CD56 and negative CD45, rhabdomyosarcoma should be included in the differential diagnosis. Here, we report an unusual case of RMS confined to the bone marrow in an older adult. [Med-Science 2018; 7(4.000): 946-8] |
| first_indexed | 2024-03-08T07:02:17Z |
| format | Article |
| id | doaj.art-f41fd39840e745f69a2999e9c6be10e0 |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T07:02:17Z |
| publishDate | 2018-12-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-f41fd39840e745f69a2999e9c6be10e02024-02-03T05:37:16ZengSociety of Turaz BilimMedicine Science2147-06342018-12-0174946810.5455/medscience.2018.07.8831295505Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphomaSinan Demircioglu0Omer EkinciAli DoganIrfan BayramCengiz DemirVan Yuzuncu Yil University, Faculty of Medicine, Department of Hematology, Van Turkey Van Yuzuncu Yil University, Faculty of Medicine, Department of Pathology, Van TurkeySome rare malignant diseases exhibit clinical features and bone marrow aspirate morphology similar to that of acute leukemia. For instance, rhabdomyosarcoma, neuroblastoma, medulloblastoma, anaplastic oligodendroglioma, small cell carcinoma, Ewings sarcoma and neuroendocrine tumors have been reported to display an acute leukemia-like morphology in bone marrow aspirates after metastasizing to the bone marrow. Rhabdomyosarcoma (RMS), a malignant tumour of mesenchymal origin which can occur at various sites in the body, is one of the most common soft tissue sarcomas in both children and adolescents, but is rare in adults with a prevalence of less than 1 %. Bone marrow metastases associated with this condition may be readily confused with acute leukemia or lymphoma. Diagnostic confirmation requires immunohistochemical and flowcytometric examinations. In patients with positive CD56 and negative CD45, rhabdomyosarcoma should be included in the differential diagnosis. Here, we report an unusual case of RMS confined to the bone marrow in an older adult. [Med-Science 2018; 7(4.000): 946-8]http://www.ejmanager.com/fulltextpdf.php?mno=295505RhabdomyosarcomaBurkitts lymphomabone marrowCD56(+)CD45(-) |
| spellingShingle | Sinan Demircioglu Omer Ekinci Ali Dogan Irfan Bayram Cengiz Demir Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma Medicine Science Rhabdomyosarcoma Burkitts lymphoma bone marrow CD56(+) CD45(-) |
| title | Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma |
| title_full | Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma |
| title_fullStr | Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma |
| title_full_unstemmed | Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma |
| title_short | Bone marrow metastasis of alveolar rhabdomyosarcoma mimicking Burkitts lymphoma |
| title_sort | bone marrow metastasis of alveolar rhabdomyosarcoma mimicking burkitts lymphoma |
| topic | Rhabdomyosarcoma Burkitts lymphoma bone marrow CD56(+) CD45(-) |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=295505 |
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