The prospects of using the silver nanoparticles composition in sodium alginate matrix

A wide range of anti-inflammatory properties of the solution of nanosilver has found its application in medical practice. In this work, nano-silver was used in the treatment of burn wounds in combination with a proteinase inhibitor. An experimental model of a second-degree burn with the use of a nan...

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Main Authors: Kubyshkin Anatoly, Pisareva Olga, Bessalova Yevgenia, Fomochkina Irina
Format: Article
Language:English
Published: EDP Sciences 2020-01-01
Series:MATEC Web of Conferences
Online Access:https://www.matec-conferences.org/articles/matecconf/pdf/2020/11/matecconf_icmsste2020_09001.pdf
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author Kubyshkin Anatoly
Pisareva Olga
Bessalova Yevgenia
Fomochkina Irina
author_facet Kubyshkin Anatoly
Pisareva Olga
Bessalova Yevgenia
Fomochkina Irina
author_sort Kubyshkin Anatoly
collection DOAJ
description A wide range of anti-inflammatory properties of the solution of nanosilver has found its application in medical practice. In this work, nano-silver was used in the treatment of burn wounds in combination with a proteinase inhibitor. An experimental model of a second-degree burn with the use of a nano-silver solution in combination therapy is accompanied by a decrease in the inhibitory potential at the local level and stimulation of regeneration processes, which indicates the anti-inflammatory effects of nano-silver particles. There is also a decrease in the morphological signs of inflammation in the burned areas of the skin of the therapeutic use of a solution of nano-silver. The results indicate that nano-silver solution for prophylactic and therapeutic use has the ability to block a cascade of inflammatory reactions in the focus of damage, as it is evidenced by a decrease in the degree of alteration and intensification of reparative processes in damaged tissues.
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spelling doaj.art-f422abd57f7b474d80e7ab85d2333c5b2022-12-21T18:40:48ZengEDP SciencesMATEC Web of Conferences2261-236X2020-01-013150900110.1051/matecconf/202031509001matecconf_icmsste2020_09001The prospects of using the silver nanoparticles composition in sodium alginate matrixKubyshkin Anatoly0Pisareva Olga1Bessalova Yevgenia2Fomochkina Irina3V. I. Vernadsky Crimean Federal University, Medical Academy Named after S.I. GeorgievskyV. I. Vernadsky Crimean Federal University, Medical Academy Named after S.I. GeorgievskyV. I. Vernadsky Crimean Federal University, Medical Academy Named after S.I. GeorgievskyV. I. Vernadsky Crimean Federal University, Medical Academy Named after S.I. GeorgievskyA wide range of anti-inflammatory properties of the solution of nanosilver has found its application in medical practice. In this work, nano-silver was used in the treatment of burn wounds in combination with a proteinase inhibitor. An experimental model of a second-degree burn with the use of a nano-silver solution in combination therapy is accompanied by a decrease in the inhibitory potential at the local level and stimulation of regeneration processes, which indicates the anti-inflammatory effects of nano-silver particles. There is also a decrease in the morphological signs of inflammation in the burned areas of the skin of the therapeutic use of a solution of nano-silver. The results indicate that nano-silver solution for prophylactic and therapeutic use has the ability to block a cascade of inflammatory reactions in the focus of damage, as it is evidenced by a decrease in the degree of alteration and intensification of reparative processes in damaged tissues.https://www.matec-conferences.org/articles/matecconf/pdf/2020/11/matecconf_icmsste2020_09001.pdf
spellingShingle Kubyshkin Anatoly
Pisareva Olga
Bessalova Yevgenia
Fomochkina Irina
The prospects of using the silver nanoparticles composition in sodium alginate matrix
MATEC Web of Conferences
title The prospects of using the silver nanoparticles composition in sodium alginate matrix
title_full The prospects of using the silver nanoparticles composition in sodium alginate matrix
title_fullStr The prospects of using the silver nanoparticles composition in sodium alginate matrix
title_full_unstemmed The prospects of using the silver nanoparticles composition in sodium alginate matrix
title_short The prospects of using the silver nanoparticles composition in sodium alginate matrix
title_sort prospects of using the silver nanoparticles composition in sodium alginate matrix
url https://www.matec-conferences.org/articles/matecconf/pdf/2020/11/matecconf_icmsste2020_09001.pdf
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