Metformin as Host-Directed Therapy for TB Treatment: Scoping Review

Metformin as Host-Directed Therapy for TB Treatment: Scoping Review

Tuberculosis (TB) disease is an international health concern caused by the bacteria Mycobacterium tuberculosis (Mtb). Evolution of multi-drug-resistant strains may cause bacterial persistence, rendering existing antibiotics ineffective. Hence, development of new or repurposing of currently approved...

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Bibliographic Details
Main Authors: Nikita Naicker, Alex Sigal, Kogieleum Naidoo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Microbiology
Subjects:
tuberculosis
metformin
host-directed therapy
Mycobacterium tuberculosis
adjuvant
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00435/full

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