Ambient Particulate Matter Induces Vascular Smooth Muscle Cell Phenotypic Changes via NOX1/ROS/NF-κB Dependent and Independent Pathways: Protective Effects of Polyphenols

Ambient Particulate Matter Induces Vascular Smooth Muscle Cell Phenotypic Changes via NOX1/ROS/NF-κB Dependent and Independent Pathways: Protective Effects of Polyphenols

Epidemiological studies have demonstrated an association between ambient particulate matter (PM) exposure and vascular diseases. Here, we observed that treatment with ambient PM increased cell migration ability in vascular smooth muscle cells (VSMCs) and pulmonary arterial SMCs (PASMCs). These resul...

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Bibliographic Details
Main Authors: Chia-Chi Ho, Yu-Cheng Chen, Ming-Hsien Tsai, Hui-Ti Tsai, Chen-Yi Weng, Shaw-Fang Yet, Pinpin Lin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antioxidants
Subjects:
ambient particulate matter
vascular phenotypic changes
migration
inflammation
oxidative stress
NADPH oxidase 1
Online Access:https://www.mdpi.com/2076-3921/10/5/782

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