Role of irisin in physiology and pathology

Role of irisin in physiology and pathology

Irisin, out-membrane part of fibronectin type III domain–containing 5 protein (FNDC5), was activated by Peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1α (PGC-1α) during physical exercise in skeletal muscle tissues. Most studies have reported that the concentration of irisin is hig...

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Bibliographic Details
Main Authors: Shiqiang Liu, Fengqi Cui, Kaiting Ning, Zhen Wang, Pengyu Fu, Dongen Wang, Huiyun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
irisin
beige fat
musculoskeletal homeostasis
cancer
liver
cardiovascular diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.962968/full

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