Synthesis of 3-Hydroxy-9<i>H</i>-fluorene-2-carboxylates via Michael Reaction, Robinson Annulation, and Aromatization

A series of 3-hydroxy-fluorene-2-carboxylate compounds were prepared from Michael addition of acetoacetate to 2-benzylideneindan-l-one followed by Robinson annulation and aromatization. In this reaction, we were able to isolate two Robinson annulation products and characterize them. This sequential...

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Bibliographic Details
Main Authors: Yu-Min Wang, Yi-Hung Liu, Shiuh-Tzung Liu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Organics
Subjects:
Online Access:https://www.mdpi.com/2673-401X/3/4/31