Obesity impacts the regulation of miR-10b and its targets in primary breast tumors

Obesity impacts the regulation of miR-10b and its targets in primary breast tumors

Abstract Background Obesity increases breast cancer (BC) risk in post-menopausal women by mostly unknown molecular mechanisms which may partly be regulated by microRNAs (miRNAs). Methods We isolated RNA from paired benign and malignant biopsies from 83 BC patients and determined miRNA profiles in sa...

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Bibliographic Details
Main Authors: Ari Meerson, Yaniv Eliraz, Hila Yehuda, Bridget Knight, Malcolm Crundwell, Douglas Ferguson, Benjamin P. Lee, Lorna W. Harries
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
miR-10b
Breast cancer
Obesity
microRNA
Tumor suppressors
Oncogenes
Online Access:http://link.springer.com/article/10.1186/s12885-019-5300-6

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