Allogeneic Mesenchymal Stem Cells Restore Endothelial Function in Heart Failure by Stimulating Endothelial Progenitor Cells

Allogeneic Mesenchymal Stem Cells Restore Endothelial Function in Heart Failure by Stimulating Endothelial Progenitor Cells

Background: Endothelial dysfunction, characterized by diminished endothelial progenitor cell (EPC) function and flow-mediated vasodilation (FMD), is a clinically significant feature of heart failure (HF). Mesenchymal stem cells (MSCs), which have pro-angiogenic properties, have the potential to rest...

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Bibliographic Details
Main Authors: Courtney Premer, Arnon Blum, Michael A. Bellio, Ivonne Hernandez Schulman, Barry E. Hurwitz, Meela Parker, Christopher R. Dermarkarian, Darcy L. DiFede, Wayne Balkan, Aisha Khan, Joshua M. Hare
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:EBioMedicine
Subjects:
Regenerative medicine
Nitric oxide
Vascular endothelium-dependent relaxation
Vasculogenesis
Autografts
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415000870

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http://www.sciencedirect.com/science/article/pii/S2352396415000870

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