7, 8, 15, 16-Tetraoxa-dispiro [5. 2. 5. 2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity

Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 strains, with N-(2-dimethylamino)ethyl-7,8,15,16-tetr...

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Bibliographic Details
Main Authors: Opsenica Igor, Terzić Nataša A., Opsenica Dejan M., Milhous Wilbur K., Šolaja Bogdan A.
Format: Article
Language:English
Published: Serbian Chemical Society 2004-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2004/0352-51390411919O.pdf