Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region
The development of 3D anthropomorphic head and neck phantoms is of crucial and timely importance to explore novel imaging techniques, such as radar-based MicroWave Imaging (MWI), which have the potential to accurately diagnose Cervical Lymph Nodes (CLNs) in a neoadjuvant and non-invasive manner. We...
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| Format: | Article |
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MDPI AG
2020-04-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/7/2029 |
| _version_ | 1797571498690478080 |
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| author | Ana Catarina Pelicano Raquel C. Conceição |
| author_facet | Ana Catarina Pelicano Raquel C. Conceição |
| author_sort | Ana Catarina Pelicano |
| collection | DOAJ |
| description | The development of 3D anthropomorphic head and neck phantoms is of crucial and timely importance to explore novel imaging techniques, such as radar-based MicroWave Imaging (MWI), which have the potential to accurately diagnose Cervical Lymph Nodes (CLNs) in a neoadjuvant and non-invasive manner. We are motivated by a significant diagnostic blind-spot regarding mass screening of LNs in the case of head and neck cancer. The timely detection and selective removal of metastatic CLNs will prevent tumor cells from entering the lymphatic and blood systems and metastasizing to other body regions. The present paper describes the developed phantom generator which allows the anthropomorphic modelling of the main biological tissues of the cervical region, including CLNs, as well as their dielectric properties, for a frequency range from 1 to 10 GHz, based on Magnetic Resonance images. The resulting phantoms of varying complexity are well-suited to contribute to all stages of the development of a radar-based MWI device capable of detecting CLNs. Simpler models are essential since complexity could hinder the initial development stages of MWI devices. Besides, the diversity of anthropomorphic phantoms resulting from the developed phantom generator can be explored in other scientific contexts and may be useful to other medical imaging modalities. |
| first_indexed | 2024-03-10T20:41:32Z |
| format | Article |
| id | doaj.art-f43071bcc5ae49d492afcbd9fcafa9c5 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T20:41:32Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-f43071bcc5ae49d492afcbd9fcafa9c52023-11-19T20:42:41ZengMDPI AGSensors1424-82202020-04-01207202910.3390/s20072029Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck RegionAna Catarina Pelicano0Raquel C. Conceição1Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, PortugalInstituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, PortugalThe development of 3D anthropomorphic head and neck phantoms is of crucial and timely importance to explore novel imaging techniques, such as radar-based MicroWave Imaging (MWI), which have the potential to accurately diagnose Cervical Lymph Nodes (CLNs) in a neoadjuvant and non-invasive manner. We are motivated by a significant diagnostic blind-spot regarding mass screening of LNs in the case of head and neck cancer. The timely detection and selective removal of metastatic CLNs will prevent tumor cells from entering the lymphatic and blood systems and metastasizing to other body regions. The present paper describes the developed phantom generator which allows the anthropomorphic modelling of the main biological tissues of the cervical region, including CLNs, as well as their dielectric properties, for a frequency range from 1 to 10 GHz, based on Magnetic Resonance images. The resulting phantoms of varying complexity are well-suited to contribute to all stages of the development of a radar-based MWI device capable of detecting CLNs. Simpler models are essential since complexity could hinder the initial development stages of MWI devices. Besides, the diversity of anthropomorphic phantoms resulting from the developed phantom generator can be explored in other scientific contexts and may be useful to other medical imaging modalities.https://www.mdpi.com/1424-8220/20/7/2029anthropomorphic phantomshead and neck modellingradar-based microwave imagingcervical lymph nodes |
| spellingShingle | Ana Catarina Pelicano Raquel C. Conceição Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region Sensors anthropomorphic phantoms head and neck modelling radar-based microwave imaging cervical lymph nodes |
| title | Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region |
| title_full | Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region |
| title_fullStr | Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region |
| title_full_unstemmed | Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region |
| title_short | Development of a 3D Anthropomorphic Phantom Generator for Microwave Imaging Applications of the Head and Neck Region |
| title_sort | development of a 3d anthropomorphic phantom generator for microwave imaging applications of the head and neck region |
| topic | anthropomorphic phantoms head and neck modelling radar-based microwave imaging cervical lymph nodes |
| url | https://www.mdpi.com/1424-8220/20/7/2029 |
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