Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli

Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli

ABSTRACT Type 4 pili (T4P) are retractable surface appendages found on numerous bacteria and archaea that play essential roles in various microbial functions, including host colonization by pathogens. An ATPase is required for T4P extension, but the mechanism by which chemical energy is transduced t...

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Bibliographic Details
Main Authors: Ashok R. Nayak, Pradip K. Singh, Jinlei Zhao, Montserrat Samsó, Michael S. Donnenberg
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
ATPase
Escherichia coli
enzyme kinetics
pili
pilus assembly
structural biology
Online Access:https://journals.asm.org/doi/10.1128/mbio.02270-22

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