Urban airborne PM2.5 induces pulmonary fibrosis through triggering glycolysis and subsequent modification of histone lactylation in macrophages

Urban airborne PM2.5 induces pulmonary fibrosis through triggering glycolysis and subsequent modification of histone lactylation in macrophages

Abstracts: Airborne fine particulate matter (PM2.5) can cause pulmonary inflammation and even fibrosis, however, the underlying molecular mechanisms of the pathogenesis of PM2.5 exposure have not been fully appreciated. In the present study, we explored the dynamics of glycolysis and modification of...

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Bibliographic Details
Main Authors: Jingyi Li, Guodong Zeng, Zezhong Zhang, Yuanli Wang, Mengyao Shao, Chunjiang Li, Zhongbing Lu, Yong Zhao, Fang Zhang, Wenjun Ding
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
Macrophage
Glycolysis
Histone lactylation
Epithelial-mesenchymal transition
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324002379

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