Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study
Abstract Background In 2015, Nigeria’s estimated 317,700 stillbirths accounted for 12.2% of the 2.6 million estimated global stillbirths. This suggests that Nigeria still makes substantial contribution to the global burden of stillbirths. This study was conducted to determine the prevalence and iden...
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| Format: | Article |
| Language: | English |
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BMC
2019-12-01
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| Series: | BMC Pregnancy and Childbirth |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12884-019-2682-z |
| _version_ | 1818938005111439360 |
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| author | Friday E. Okonofua Lorretta Favour C. Ntoimo Rosemary Ogu Hadiza Galadanci Gana Mohammed Durodola Adetoye Eghe Abe Ola Okike Kingsley Agholor Rukiyat Abdus-salam Abdullahi Randawa |
| author_facet | Friday E. Okonofua Lorretta Favour C. Ntoimo Rosemary Ogu Hadiza Galadanci Gana Mohammed Durodola Adetoye Eghe Abe Ola Okike Kingsley Agholor Rukiyat Abdus-salam Abdullahi Randawa |
| author_sort | Friday E. Okonofua |
| collection | DOAJ |
| description | Abstract Background In 2015, Nigeria’s estimated 317,700 stillbirths accounted for 12.2% of the 2.6 million estimated global stillbirths. This suggests that Nigeria still makes substantial contribution to the global burden of stillbirths. This study was conducted to determine the prevalence and identify the causes and factors associated with stillbirth in eight referral hospitals in Nigeria. Methods This was a cross-sectional study of all deliveries over a period of 6 months in six general hospitals (4 in the south and 2 in the north), and two teaching hospitals (both in the north) in Nigeria. The study population was women delivering in the hospitals during the study period. A pre-tested study protocol was used to obtain clinical data on pregnancies, live births and stillbirths in the hospitals over a 6 months period. Data were analyzed centrally using univariate, bivariate and multivariate logistic regression analyses. The main outcome measure was stillbirth rate in the hospitals (individually and overall). Results There were 4416 single births and 175 stillbirths, and a mean stillbirth rate of 39.6 per 1000 births (range: 12.7 to 67.3/1000 births) in the hospitals. Antepartum (macerated) constituted 22.3% of the stillbirths; 47.4% were intrapartum (fresh stillbirths); while 30.3% was unclassified. Acute hypoxia accounted for 32.6% of the stillbirths. Other causes were maternal hypertensive disease (6.9%), and intrapartum unexplained (5.7%) among others. After adjusting for confounding variables, significant predictors of stillbirth were referral status, parity, past experience of stillbirth, birth weight, gestational age at delivery and mode of delivery. Conclusion We conclude that the rate of stillbirth is high in Nigeria’s referral hospitals largely because of patients’ related factors and the high rates of pregnancy complications. Efforts to address these factors through improved patients’ education and emergency obstetric care would reduce the rate of stillbirth in the country. Trial registration Trial Registration Number NCTR91540209. Nigeria Clinical Trials Registry. http://www.nctr.nhrec.net/ Registered April 14th 2016. |
| first_indexed | 2024-12-20T06:00:58Z |
| format | Article |
| id | doaj.art-f4377449271e4005aa426e559ecc116c |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-20T06:00:58Z |
| publishDate | 2019-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-f4377449271e4005aa426e559ecc116c2022-12-21T19:50:55ZengBMCBMC Pregnancy and Childbirth1471-23932019-12-011911910.1186/s12884-019-2682-zPrevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre studyFriday E. Okonofua0Lorretta Favour C. Ntoimo1Rosemary Ogu2Hadiza Galadanci3Gana Mohammed4Durodola Adetoye5Eghe Abe6Ola Okike7Kingsley Agholor8Rukiyat Abdus-salam9Abdullahi Randawa10Women’s Health and Action Research Centre/WHO Implementation Research GroupWomen’s Health and Action Research Centre/WHO Implementation Research GroupWomen’s Health and Action Research Centre/WHO Implementation Research GroupAminu Kano Teaching HospitalGeneral HospitalGeneral HospitalCentral HospitalKarshi General Hospital, Federal Capital TerritoryCentral HospitalAdeoyo Maternity HospitalAhmadu Bello University Teaching HospitalAbstract Background In 2015, Nigeria’s estimated 317,700 stillbirths accounted for 12.2% of the 2.6 million estimated global stillbirths. This suggests that Nigeria still makes substantial contribution to the global burden of stillbirths. This study was conducted to determine the prevalence and identify the causes and factors associated with stillbirth in eight referral hospitals in Nigeria. Methods This was a cross-sectional study of all deliveries over a period of 6 months in six general hospitals (4 in the south and 2 in the north), and two teaching hospitals (both in the north) in Nigeria. The study population was women delivering in the hospitals during the study period. A pre-tested study protocol was used to obtain clinical data on pregnancies, live births and stillbirths in the hospitals over a 6 months period. Data were analyzed centrally using univariate, bivariate and multivariate logistic regression analyses. The main outcome measure was stillbirth rate in the hospitals (individually and overall). Results There were 4416 single births and 175 stillbirths, and a mean stillbirth rate of 39.6 per 1000 births (range: 12.7 to 67.3/1000 births) in the hospitals. Antepartum (macerated) constituted 22.3% of the stillbirths; 47.4% were intrapartum (fresh stillbirths); while 30.3% was unclassified. Acute hypoxia accounted for 32.6% of the stillbirths. Other causes were maternal hypertensive disease (6.9%), and intrapartum unexplained (5.7%) among others. After adjusting for confounding variables, significant predictors of stillbirth were referral status, parity, past experience of stillbirth, birth weight, gestational age at delivery and mode of delivery. Conclusion We conclude that the rate of stillbirth is high in Nigeria’s referral hospitals largely because of patients’ related factors and the high rates of pregnancy complications. Efforts to address these factors through improved patients’ education and emergency obstetric care would reduce the rate of stillbirth in the country. Trial registration Trial Registration Number NCTR91540209. Nigeria Clinical Trials Registry. http://www.nctr.nhrec.net/ Registered April 14th 2016.https://doi.org/10.1186/s12884-019-2682-zStillbirthStillbirth rateReferral hospitalsCaesarean sectionNigerian women |
| spellingShingle | Friday E. Okonofua Lorretta Favour C. Ntoimo Rosemary Ogu Hadiza Galadanci Gana Mohammed Durodola Adetoye Eghe Abe Ola Okike Kingsley Agholor Rukiyat Abdus-salam Abdullahi Randawa Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study BMC Pregnancy and Childbirth Stillbirth Stillbirth rate Referral hospitals Caesarean section Nigerian women |
| title | Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study |
| title_full | Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study |
| title_fullStr | Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study |
| title_full_unstemmed | Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study |
| title_short | Prevalence and determinants of stillbirth in Nigerian referral hospitals: a multicentre study |
| title_sort | prevalence and determinants of stillbirth in nigerian referral hospitals a multicentre study |
| topic | Stillbirth Stillbirth rate Referral hospitals Caesarean section Nigerian women |
| url | https://doi.org/10.1186/s12884-019-2682-z |
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