Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review

Purpose of ReviewIn this review, we summarize ethnic/race- and age-related variation in AMH and discuss the underpinnings behind these differences.Recent findingsAnti-mullerian hormone (AMH) has become a widely used method of ovarian reserve testing over the last 15 years. Numerous studies have show...

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Main Authors: Alexander M. Kotlyar, David B. Seifer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.593216/full
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author Alexander M. Kotlyar
David B. Seifer
author_facet Alexander M. Kotlyar
David B. Seifer
author_sort Alexander M. Kotlyar
collection DOAJ
description Purpose of ReviewIn this review, we summarize ethnic/race- and age-related variation in AMH and discuss the underpinnings behind these differences.Recent findingsAnti-mullerian hormone (AMH) has become a widely used method of ovarian reserve testing over the last 15 years. Numerous studies have shown substantial ethnic/race and age-related differences. When compared to age-matched Caucasian women, AMH levels tend to be lower in black and Hispanic women. Chinese women tend to have significantly greater AMH levels prior to age 25 than Caucasian women. When considering subpopulations within ethnicities, at least one study noted lower AMH levels among Maya women compared to other Hispanic women. Age exhibits a positive trend with AMH up until at least 25 years of age with a consistent decline after 34 years of age extending to menopause.SummaryAMH levels are highly variable among ethnicities and race with higher age-matched levels typically seen in Caucasian women. Age does not exhibit a consistent linear relationship with AMH, but a consistent decline is seen starting in the third decade of life and proceeding to menopause.
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spelling doaj.art-f43cdfed0b6e473098a796d35562916f2022-12-21T23:02:06ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922021-02-011110.3389/fendo.2020.593216593216Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A ReviewAlexander M. KotlyarDavid B. SeiferPurpose of ReviewIn this review, we summarize ethnic/race- and age-related variation in AMH and discuss the underpinnings behind these differences.Recent findingsAnti-mullerian hormone (AMH) has become a widely used method of ovarian reserve testing over the last 15 years. Numerous studies have shown substantial ethnic/race and age-related differences. When compared to age-matched Caucasian women, AMH levels tend to be lower in black and Hispanic women. Chinese women tend to have significantly greater AMH levels prior to age 25 than Caucasian women. When considering subpopulations within ethnicities, at least one study noted lower AMH levels among Maya women compared to other Hispanic women. Age exhibits a positive trend with AMH up until at least 25 years of age with a consistent decline after 34 years of age extending to menopause.SummaryAMH levels are highly variable among ethnicities and race with higher age-matched levels typically seen in Caucasian women. Age does not exhibit a consistent linear relationship with AMH, but a consistent decline is seen starting in the third decade of life and proceeding to menopause.https://www.frontiersin.org/articles/10.3389/fendo.2020.593216/fullovarian reserveageraceethnicityAMHage-specific AMH levels
spellingShingle Alexander M. Kotlyar
David B. Seifer
Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
Frontiers in Endocrinology
ovarian reserve
age
race
ethnicity
AMH
age-specific AMH levels
title Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
title_full Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
title_fullStr Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
title_full_unstemmed Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
title_short Ethnicity/Race and Age-Specific Variations of Serum AMH in Women—A Review
title_sort ethnicity race and age specific variations of serum amh in women a review
topic ovarian reserve
age
race
ethnicity
AMH
age-specific AMH levels
url https://www.frontiersin.org/articles/10.3389/fendo.2020.593216/full
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