Immune System Alterations in Multiple Myeloma: Molecular Mechanisms and Therapeutic Strategies to Reverse Immunosuppression

Immune System Alterations in Multiple Myeloma: Molecular Mechanisms and Therapeutic Strategies to Reverse Immunosuppression

Immunosuppression is a common feature of multiple myeloma (MM) patients and has been associated with disease evolution from its precursor stages. MM cells promote immunosuppressive effects due to both the secretion of soluble factors, which inhibit the function of immune effector cells, and the recr...

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Bibliographic Details
Main Authors: Andrea Díaz-Tejedor, Mauro Lorenzo-Mohamed, Noemí Puig, Ramón García-Sanz, María-Victoria Mateos, Mercedes Garayoa, Teresa Paíno
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
multiple myeloma
immune system
immunosuppression
monoclonal antibodies
immune stimulating drugs
Online Access:https://www.mdpi.com/2072-6694/13/6/1353

Internet

https://www.mdpi.com/2072-6694/13/6/1353

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