SPARC Inhibits LPA-Mediated Mesothelial—Ovarian Cancer Cell Crosstalk

SPARC Inhibits LPA-Mediated Mesothelial—Ovarian Cancer Cell Crosstalk

The interplay between peritoneal mesothelial cells and ovarian cancer cells is critical for the initiation and peritoneal dissemination of, and ascites formation in, ovarian cancer. The production of lysophosphatidic acid (LPA) by both peritoneal mesothelial cells and ovarian cancer cells has been s...

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Bibliographic Details
Main Authors: Neveen A. Said, Ida Najwer, Matthew J. Socha, David J. Fulton, Samuel C. Mok, Kouros Motamed
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
SPARC
LPA
IL-6
ovarian cancer
mesothelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800133

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