Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments
Abstract The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseudorabies, responsible for severe economic losses to the swine industry worldwide. The interferon-inducible GTPase guanylate-binding protein 1 (GBP1) exhibits antiviral immunity. Our findings show that there is a rob...
Main Authors: | Xiaohua Zhang, Qian Du, Guiyuan Chen, Yiyuan Jiang, Kai Huang, Linghao Li, Dewen Tong, Yong Huang |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Veterinary Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13567-023-01154-0 |
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