Zika virus infection triggers lipophagy by stimulating the AMPK-ULK1 signaling in human hepatoma cells

Zika virus infection triggers lipophagy by stimulating the AMPK-ULK1 signaling in human hepatoma cells

Zika virus (ZIKV) is a globally transmitted mosquito-borne pathogen, and no effective treatment or vaccine is available yet. Lipophagy, a selective autophagy targeting lipid droplets (LDs), is an emerging subject in cellular lipid metabolism and energy homeostasis. However, the regulatory mechanism...

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Bibliographic Details
Main Authors: Zhao-Ling Qin, Qiu-Feng Yao, Ping Zhao, Hao Ren, Zhong-Tian Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Zika virus
lipophagy
AMPK
ULK1
mTOR
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.959029/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.959029/full

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