Acute Kidney Injury with SARS-CoV-2 Infection in Pediatric Patients Receiving High-Dose Methotrexate Chemotherapy: A Report of Three Cases

Acute Kidney Injury with SARS-CoV-2 Infection in Pediatric Patients Receiving High-Dose Methotrexate Chemotherapy: A Report of Three Cases

Background. Methotrexate is renally excreted. HDMTX (high dose-methotrexate)-induced acute kidney injury (AKI) is a non-oliguric decrease in glomerular filtration rate (GFR) heralded by an acute rise in serum creatinine. Moreover, AKI is also a frequent complication of COVID-19. Among our patients t...

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Bibliographic Details
Main Authors: Olga Nigro, Cristina Meazza, Elisabetta Schiavello, Veronica Biassoni, Nadia Puma, Luca Bergamaschi, Giovanna Gattuso, Giovanna Sironi, Virginia Livellara, Gabriele Papagni, Maura Massimino
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Children
Subjects:
SARS-CoV-2
COVID-19
methotrexate
pediatric
renal failure
AKI
Online Access:https://www.mdpi.com/2227-9067/10/2/331

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