ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN

Reducing pain is the first phase of treatment in dentistry. Pain can be reduced by application of peroral analgetic medicines such as paracetamol, although on certain circumstances such as pulpitis paim, this is less helpful. Dentists often use eugenol to alleviate acute pulpitis pain, while latex o...

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Main Author: Indrya Kirana Mattulada
Format: Article
Language:English
Published: Faculty of Dentistry, Universitas Indonesia 2015-06-01
Series:Journal of Dentistry Indonesia
Subjects:
Online Access:http://jdentistry.ui.ac.id/index.php/JDI/article/view/312
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author Indrya Kirana Mattulada
author_facet Indrya Kirana Mattulada
author_sort Indrya Kirana Mattulada
collection DOAJ
description Reducing pain is the first phase of treatment in dentistry. Pain can be reduced by application of peroral analgetic medicines such as paracetamol, although on certain circumstances such as pulpitis paim, this is less helpful. Dentists often use eugenol to alleviate acute pulpitis pain, while latex of Jaropha curcas is one of the most popular analgetic agent used by people. The objective of this study was to compare the analgetic effect of the latex of J. curcas with paracetamol by the hot plate test. Thirty male mices aged 2 – 3 months old, weight 20 -30 gram were divided into 5 groups. The lyophilized latex of J. curcas was diluted into 5, 10, and 15% respectively, and the dose was 5 mg/Kg BW. The dose of paracetamol (positive control) was 1,3 mg/Kg BW and sterile aquabidest (negative control) was 1,3 mg/Kg BW. All agents were administered orally. Analgetic activity was evaluated after 3, 6, and 24 hours. The test was considered positive if the latent time of the test group was equal or 3 times higher than the control group. Data was analyzed by 1-way Anova. Had it been a difference, research would be continued using HSD test (p,0,05). Latex of J. curcas has the same analgetic effect as paracetamol on 3 and 6 hours observation, but was reduced on 24 hours observation.
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spelling doaj.art-f445d4c50c5e4ac791200038fe713f422022-12-22T03:25:22ZengFaculty of Dentistry, Universitas IndonesiaJournal of Dentistry Indonesia1693-96972355-48002015-06-0113220620910.14693/jdi.v13i2.312226ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAINIndrya Kirana Mattulada0Department of Conservative Dentistry, Faculty of Dentistry, Universitas HasanudinReducing pain is the first phase of treatment in dentistry. Pain can be reduced by application of peroral analgetic medicines such as paracetamol, although on certain circumstances such as pulpitis paim, this is less helpful. Dentists often use eugenol to alleviate acute pulpitis pain, while latex of Jaropha curcas is one of the most popular analgetic agent used by people. The objective of this study was to compare the analgetic effect of the latex of J. curcas with paracetamol by the hot plate test. Thirty male mices aged 2 – 3 months old, weight 20 -30 gram were divided into 5 groups. The lyophilized latex of J. curcas was diluted into 5, 10, and 15% respectively, and the dose was 5 mg/Kg BW. The dose of paracetamol (positive control) was 1,3 mg/Kg BW and sterile aquabidest (negative control) was 1,3 mg/Kg BW. All agents were administered orally. Analgetic activity was evaluated after 3, 6, and 24 hours. The test was considered positive if the latent time of the test group was equal or 3 times higher than the control group. Data was analyzed by 1-way Anova. Had it been a difference, research would be continued using HSD test (p,0,05). Latex of J. curcas has the same analgetic effect as paracetamol on 3 and 6 hours observation, but was reduced on 24 hours observation.http://jdentistry.ui.ac.id/index.php/JDI/article/view/312Painlatex of J. curcas
spellingShingle Indrya Kirana Mattulada
ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN
Journal of Dentistry Indonesia
Pain
latex of J. curcas
title ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN
title_full ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN
title_fullStr ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN
title_full_unstemmed ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN
title_short ANALGETIC EFFECT OF J. CURCAS ON ACUTE DENTAL PAIN
title_sort analgetic effect of j curcas on acute dental pain
topic Pain
latex of J. curcas
url http://jdentistry.ui.ac.id/index.php/JDI/article/view/312
work_keys_str_mv AT indryakiranamattulada analgeticeffectofjcurcasonacutedentalpain