Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report

Key Clinical Message Neurogenic fever (NF) is a potentially life‐threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF. Abstract Neurogenic fever (NF)...

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Main Authors: Saroj Poudel, Rupak Chalise, Manoj Bist, Ashim Regmi, Anup Ghimire, Kishor Khanal
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.7956
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author Saroj Poudel
Rupak Chalise
Manoj Bist
Ashim Regmi
Anup Ghimire
Kishor Khanal
author_facet Saroj Poudel
Rupak Chalise
Manoj Bist
Ashim Regmi
Anup Ghimire
Kishor Khanal
author_sort Saroj Poudel
collection DOAJ
description Key Clinical Message Neurogenic fever (NF) is a potentially life‐threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF. Abstract Neurogenic fever (NF) is a common complication following pontine hemorrhage and poses significant challenges for clinicians in terms of diagnosis, management, and patient outcomes. This study delves into the efficacy of treatment methods involving baclofen and propranolol for neurogenic fever in patients with pontine hemorrhage. The results demonstrated a significant reduction in the duration and intensity of fever. Moreover, the treatment modality was well‐tolerated and devoid of any adverse effects. These findings suggest that the use of oral baclofen and propranolol may be a promising therapeutic option for managing neurogenic fever in patients with pontine hemorrhage.
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spelling doaj.art-f446cc66b0014a9297069c4621f777e72023-10-20T06:16:22ZengWileyClinical Case Reports2050-09042023-09-01119n/an/a10.1002/ccr3.7956Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case reportSaroj Poudel0Rupak Chalise1Manoj Bist2Ashim Regmi3Anup Ghimire4Kishor Khanal5Critical Care Medicine Nepal Mediciti Lalitpur NepalCritical Care Medicine Nepal Mediciti Lalitpur NepalCritical Care Medicine Nepal Mediciti Lalitpur NepalCritical Care Medicine Nepal Mediciti Lalitpur NepalCritical Care Medicine Nepal Mediciti Lalitpur NepalCritical Care Medicine Nepal Mediciti Lalitpur NepalKey Clinical Message Neurogenic fever (NF) is a potentially life‐threatening complication commonly seen in patients with pontine hemorrhage. This case report highlights the successful use of oral baclofen and propranolol as an effective treatment strategy to manage NF. Abstract Neurogenic fever (NF) is a common complication following pontine hemorrhage and poses significant challenges for clinicians in terms of diagnosis, management, and patient outcomes. This study delves into the efficacy of treatment methods involving baclofen and propranolol for neurogenic fever in patients with pontine hemorrhage. The results demonstrated a significant reduction in the duration and intensity of fever. Moreover, the treatment modality was well‐tolerated and devoid of any adverse effects. These findings suggest that the use of oral baclofen and propranolol may be a promising therapeutic option for managing neurogenic fever in patients with pontine hemorrhage.https://doi.org/10.1002/ccr3.7956baclofencentral hyperpyrexianeurogenic feverpontine hemorrhagepropranolol
spellingShingle Saroj Poudel
Rupak Chalise
Manoj Bist
Ashim Regmi
Anup Ghimire
Kishor Khanal
Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
Clinical Case Reports
baclofen
central hyperpyrexia
neurogenic fever
pontine hemorrhage
propranolol
title Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_full Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_fullStr Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_full_unstemmed Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_short Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
title_sort use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage a case report
topic baclofen
central hyperpyrexia
neurogenic fever
pontine hemorrhage
propranolol
url https://doi.org/10.1002/ccr3.7956
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