Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry
The study sought to assess the procedural success of rotational atherectomy (RA) in coronary chronic total occlusion (CTO) and to investigate the in-hospital and one-year outcomes following RA. From 2015 to 2019, patients undergoing percutaneous coronary intervention for CTO (CTO PCI) were retrospec...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/10/3510 |
| _version_ | 1797599633433690112 |
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| author | Mohamed Ayoub Noé Corpataux Michael Behnes Tobias Schupp Jan Forner Ibrahim Akin Franz-Josef Neumann Dirk Westermann Volker Rudolph Kambis Mashayekhi |
| author_facet | Mohamed Ayoub Noé Corpataux Michael Behnes Tobias Schupp Jan Forner Ibrahim Akin Franz-Josef Neumann Dirk Westermann Volker Rudolph Kambis Mashayekhi |
| author_sort | Mohamed Ayoub |
| collection | DOAJ |
| description | The study sought to assess the procedural success of rotational atherectomy (RA) in coronary chronic total occlusion (CTO) and to investigate the in-hospital and one-year outcomes following RA. From 2015 to 2019, patients undergoing percutaneous coronary intervention for CTO (CTO PCI) were retrospectively included into the hospital database. The primary endpoint was procedural success. Secondary endpoints were in-hospital and one-year major adverse cardiovascular and cerebral event (MACCE) rates. During the study period of 5 years, 2.789 patients underwent CTO PCI. Patients treated with RA (<i>n</i> = 193, 6.92%) had a significantly higher procedural success (93.26% vs. 85.10%, <i>p</i> = 0.0002) compared to those treated without RA (<i>n</i> = 2.596, 93.08%). Despite a significantly higher rate of pericardiocentesis (3.11% vs. 0.50%, <i>p</i> = 0.0013) in the RA group, the in-hospital and one-year MACCE rate was similar in both groups (4.15% vs. 2.77%, <i>p</i> = 0.2612; 18.65% vs. 16.72%, <i>p</i> = 0.485). In conclusion, RA is associated with higher procedural success for CTO PCI, but has higher risks for pericardial tamponade than CTO PCI without the need for RA. Nevertheless, in-hospital and one-year MACCE rates did not differ in-between both groups. |
| first_indexed | 2024-03-11T03:38:04Z |
| format | Article |
| id | doaj.art-f44ca909f2974e80b477117d046cd4c1 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T03:38:04Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-f44ca909f2974e80b477117d046cd4c12023-11-18T01:54:15ZengMDPI AGJournal of Clinical Medicine2077-03832023-05-011210351010.3390/jcm12103510Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational RegistryMohamed Ayoub0Noé Corpataux1Michael Behnes2Tobias Schupp3Jan Forner4Ibrahim Akin5Franz-Josef Neumann6Dirk Westermann7Volker Rudolph8Kambis Mashayekhi9Division of Cardiology and Angiology, Heart Center University of Bochum, 32545 Bad Oeynhausen, GermanyDepartment of Cardiology, Bern University Hospital, University of Bern, 3010 Bern, SwitzerlandDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, 68167 Mannheim, GermanyDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, 68167 Mannheim, GermanyDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, 68167 Mannheim, GermanyDepartment of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, University Medical Centre Mannheim, Medical Faculty Mannheim, 68167 Mannheim, GermanyDepartment of Cardiology and Angiology II, University Heart Center Freiburg, 79189 Bad Krozingen, GermanyDepartment of Cardiology and Angiology II, University Heart Center Freiburg, 79189 Bad Krozingen, GermanyDivision of Cardiology and Angiology, Heart Center University of Bochum, 32545 Bad Oeynhausen, GermanyDepartment of Cardiology and Angiology II, University Heart Center Freiburg, 79189 Bad Krozingen, GermanyThe study sought to assess the procedural success of rotational atherectomy (RA) in coronary chronic total occlusion (CTO) and to investigate the in-hospital and one-year outcomes following RA. From 2015 to 2019, patients undergoing percutaneous coronary intervention for CTO (CTO PCI) were retrospectively included into the hospital database. The primary endpoint was procedural success. Secondary endpoints were in-hospital and one-year major adverse cardiovascular and cerebral event (MACCE) rates. During the study period of 5 years, 2.789 patients underwent CTO PCI. Patients treated with RA (<i>n</i> = 193, 6.92%) had a significantly higher procedural success (93.26% vs. 85.10%, <i>p</i> = 0.0002) compared to those treated without RA (<i>n</i> = 2.596, 93.08%). Despite a significantly higher rate of pericardiocentesis (3.11% vs. 0.50%, <i>p</i> = 0.0013) in the RA group, the in-hospital and one-year MACCE rate was similar in both groups (4.15% vs. 2.77%, <i>p</i> = 0.2612; 18.65% vs. 16.72%, <i>p</i> = 0.485). In conclusion, RA is associated with higher procedural success for CTO PCI, but has higher risks for pericardial tamponade than CTO PCI without the need for RA. Nevertheless, in-hospital and one-year MACCE rates did not differ in-between both groups.https://www.mdpi.com/2077-0383/12/10/3510coronary chronic total occlusionCTOrotational atherectomypercutaneous coronary interventioncoronary artery disease |
| spellingShingle | Mohamed Ayoub Noé Corpataux Michael Behnes Tobias Schupp Jan Forner Ibrahim Akin Franz-Josef Neumann Dirk Westermann Volker Rudolph Kambis Mashayekhi Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry Journal of Clinical Medicine coronary chronic total occlusion CTO rotational atherectomy percutaneous coronary intervention coronary artery disease |
| title | Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry |
| title_full | Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry |
| title_fullStr | Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry |
| title_full_unstemmed | Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry |
| title_short | Safety and Efficiency of Rotational Atherectomy in Chronic Total Coronary Occlusion—One-Year Clinical Outcomes of an Observational Registry |
| title_sort | safety and efficiency of rotational atherectomy in chronic total coronary occlusion one year clinical outcomes of an observational registry |
| topic | coronary chronic total occlusion CTO rotational atherectomy percutaneous coronary intervention coronary artery disease |
| url | https://www.mdpi.com/2077-0383/12/10/3510 |
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